ABSTRACT

Presents authoritative state-of-the-art discussions of the key issues pertinent to transdermal drug delivery, examining those topics necessary to enable a critical evaluation of a drug candidate's potential to be delivered across the skin; from physical chemistry and assessment of drug permeability to available enhancement technolgies, to regulator

chapter 2|31 pages

Evaluating the Transdermal Permeability of Chemicals

ByBrent E. Vecchia, Annette L. Bunge

chapter 3|85 pages

Skin Absorption Databases and Predictive Equations

ByBrent E. Vecchia, Annette L. Bunge

chapter 4|56 pages

Partitioning of Chemicals into Skin: Results and Predictions

ByBrent E. Vecchia, Annette L. Bunge

chapter 5|26 pages

Iontophoresis: Applications in Drug Delivery and Noninvasive Monitoring *

ByM. Begoña Delgado-Charro, Richard H. Guy

chapter 6|28 pages

Skin Electroporation for Transdermal and Topical Drug Delivery

ByVéronique Préat, Rita Vanbever

chapter 7|30 pages

Sonophoresis: Ultrasound-Enhanced Transdermal Drug Delivery

ByVictor Meidan

chapter 8|20 pages

Metabolic Approach to Transdermal Drug Delivery

ByPeter M. Elias, Kenneth R. Feingold, Janice Tsai, Carl Thornfeldt, Gopinathan Menon

chapter 9|22 pages

The Application of Supersaturated Systems to Percutaneous Drug Delivery

ByMark Pellett, S. Lakshmi Raghavan, Jonathan Hadgraft, Adrian Davis

chapter 10|29 pages

Minimally Invasive Systems for Transdermal Drug Delivery

ByJames A. Down, Noel G. Harvey

chapter 11|6 pages

Transdermal Drug Delivery System Regulatory Issues

ByVinod P. Shah