ABSTRACT

Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programs, and in particular the key role that comparative genomics and proteomics play within this strategy. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds.

chapter 1|24 pages

Comparative genomics and drug discovery in trypanosomatids

BySergio Callejas, Sara Melville

chapter 2|21 pages

The practical implications of comparative kinetoplastid genomics

ByC. S. Peacock

chapter 3|45 pages

The relevance of host genes in malaria

ByMiguel Prudêncio, Cristina D. Rodrigues, Maria M. Mota

chapter 4|21 pages

Nicotinic acetylcholine receptors as drug/chemical targets, contributions from comparative genomics, forward and reverse genetics

ByDavid B. Sattelle, Andrew K. Jones, Laurence A. Brown, Steven D. Buckingham, Christopher J. Mee, Luanda Pym

chapter 6|11 pages

‘Omics’ in translational medicine: are they lost in translation?

ByJohn A. Bilello