ABSTRACT

The prevalence of coronary artery disease is increasing due to rising rates of obesity and the fact that a greater number of people are living longer. Coronary Atherosclerosis: Current Management and Treatment addresses this leading cause of death worldwide.



Atherosclerosis has a broad range of disease manifestations depending on the degree of the stenosis and the functional status of the coronary plaque. This volume, written by a leading international team of editors, addresses the pathophysiology of the disease, established and novel diagnostic approaches (both invasive and non-invasive), treatment methodologies (including treatment algorithms), and differing perspectives on treatment, including future therapies and long-term outcomes. The inclusion of personal perspectives from experts, full-color images and ancillary video files make this a key resource.



Key topics include:









  • Pharmacology of coronary artery disease (CAD)


  • Up-to-date evidence on pathophysiology


  • Invasive and non-invasive imaging


  • Current evidence for risk stratification


  • Clinical decisionmaking






Coronary Atherosclerosis: Current Management and Treatment provides a state-of-the-art review of current knowledge to aid specialists, general physicians, and cardiologists in training, in the diagnosis, risk stratification, and management of patients with diverse presentations of coronary atherosclerosis.

chapter 1|10 pages

Current concepts of plaque formation and the progression of atherosclerosis

ByMasataka Nakano, Renu Virmani, Frank D. Kolodgie

chapter 6|13 pages

Clinical evaluation of the patient with chest pain

ByAttilio Maseri

chapter 7|10 pages

Exercise stress testing, stress echocardiography, and scintigraphy: Which tool for which patient?

ByArend F.L. Schinkel and Manolis Bountioukos

chapter 8|14 pages

Multislice computed tomography: Role in diagnosis and risk stratification

ByGert-Jan R. ten Kate, Koen Nieman, and Pim J. de Feyter

chapter 9|11 pages

Magnetic resonance imaging: Role in diagnosis and risk stratification

ByPier Giorgio Masci, Jan Bogaert

chapter 10|18 pages

PET-CT: Role in diagnosis and potential to predict the response to revascularization

ByAngela S. Koh, Marcelo F. Di Carli

chapter 12|12 pages

Fractional flow reserve: Role in guiding clinical decision making

ByAaron Peace, Stylianos A. Pyxaras, Bernard De Bruyne

chapter 13|14 pages

Intravascular ultrasound: Role in patient diagnosis and management

ByKenji Sakamoto, Yasuhiro Honda, Peter J. Fitzgerald

chapter 14|9 pages

Photoacoustic imaging of coronary arteries: Current status and potential clinical applications

ByKrista Jansen, Gijs van Soest, Ton van der Steen

chapter 21|9 pages

What is the optimal imaging tool for coronary atherosclerosis?

ByTakashi Kubo, Takashi Akasaka

chapter 22|19 pages

Optimization of primary and secondary prevention

ByKaterina K. Naka, Aris Bechlioulis, Lampros K. Michalis

chapter 23|9 pages

Anti-ischemic pharmacotherapy in patients with established coronary artery disease

ByDimitrios Alexopoulos, Ioanna Xanthopoulou

chapter 24|15 pages

Antithrombotic pharmacotherapy in patients with established coronary artery disease

ByAntonio Tello-Montoliu, Dominick J. Angiolillo

chapter 25|10 pages

Invasive assessment and management of intermediate coronary narrowings

ByWilliam F. Fearon

chapter 26|19 pages

Treatment algorithm in patients with stable angina

ByAndrew Cassar, Bernard J. Gersh

chapter 27|16 pages

Treatment algorithm in patients with NSTEMI and unstable angina

ByFrancesco Saia

chapter 28|12 pages

Treatment algorithm in patients with STEMI

ByLuca Golino, Giuseppe De Luca

chapter 29|9 pages

Management of microvascular angina

ByJuan Carlos Kaski, Peter Ong

chapter 30|9 pages

Treatment algorithm in patients with concomitant heart valve disease

ByVassilis Voudris, Panagiota Georgiadou

chapter 31|8 pages

Clinical perspectives on the management of advanced stable coronary disease

ByRanil de Silva and Kim Fox

chapter 32|9 pages

Interventional perspectives on the management of advanced stable coronary artery disease

ByJoanne Shannon, Azeem Latib, Antonio Colombo

chapter 33|9 pages

Surgical perspectives on the management of advanced stable coronary artery disease

ByMichael Mack, Stuart J. Head, A. Pieter Kappetein

chapter 34|12 pages

Hybrid treatments and future perspectives

ByG. Russell Reiss, Mathew R. Williams

chapter 36|6 pages

Determinants of long-term outcome following bypass surgery

ByA. Pieter Kappetein, Stuart J. Head

chapter 37|13 pages

Novel therapeutic approaches to prevention and regression of atherosclerosis

Kuang-Yuh Chyu and Prediman K. Shah
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