The ability to regulate cell volume in the face of osmotic challenge is one of the most fundamental of cellular homeostatic mechanisms. Cellular and Molecular Physiology of Cell Volume Regulation is an integrated collection of articles describing key aspects of cell volume control. The book has been organized around concepts and cellular/molecular processes rather than around mechanisms of volume regulation in specific cell types in order to make it more accessible to a multidisciplinary audience of students, instructors, and researchers.

part Part I|77 pages

Fundamental Principles and Physiological Roles of Cell Volume Regulation

chapter Chapter 1|27 pages

Principles of Cell Volume Regulation

ByKenneth R. Hallows, Philip A. Knauf

chapter Chapter 2|17 pages

Volume Regulation in Epithelia: Transcellular Transport and Cross-Talk

ByLuis Reuss, Calvin U. Cotton

chapter Chapter 3|14 pages

Volume Regulation in Renal Medullary Nephron Segments

ByAdam M. Sun, Steven C. Hebert

chapter Chapter 4|15 pages

Clinical Significance of Cellular Osmoregulation

ByMichael L. McManus, Kevin B. Churchwell

part Part II|66 pages

Organic Osmolytes

chapter Chapter 5|29 pages

Compatible and Counteracting Solutes

ByPaul H. Yancey

chapter Chapter 6|12 pages

Regulation of Cellular Amino Acid Levels

ByJ. S. Ballantyne, M. E. Chamberlin

chapter Chapter 7|10 pages

The Role and Regulation of Methylamines in the Response of Cells to Osmotic Stress

ByJulia Dragolovich, Sidney K. Pierce

chapter Chapter 8|12 pages

Regulation of Intracellular Polyols and Sugars in Response to Osmotic Stress

ByJeff M. Sands

part Part III|177 pages

Volume Sensing and Signal Transduction

chapter Chapter 9|34 pages

Cellular Signal Transduction Mechanisms

ByThomas Force, Joseph V. Bonventre

chapter Chapter 13|26 pages

Stretch-Activated Ion Channels

ByHenry Sackin

chapter Chapter 14|18 pages

The Cytoskeleton and Cell Volume Regulation

ByJohn W. Mills, Erik M. Schwiebert, Bruce A. Stanton

chapter Chapter 15|19 pages

The Role of Calcium in the Control of Volume-Regulatory Transport Pathways

ByJ. Kevin Foskett

chapter Chapter 16|20 pages

Eicosanoids and Cell Volume Regulation

ByIan Henry Lambert

chapter Chapter 17|12 pages

Involvement of a G Protein in the Shrinkage-Induced Activation of Na-H Exchange in Barnacle Muscle Fibers

ByWalter F. Boron, Emilia M. Hogan, Bruce A. Davis

chapter Chapter 18|11 pages

Coordinated Regulation of Volume-Activated Transport Pathways

ByJohn C. Parker

part Part IV|72 pages

Role of Gene Expression in Cell Volume Control

chapter Chapter 19|10 pages

Regulation of Eukaryotic Gene Expression

ByArlyn García-Pérez

chapter Chapter 20|12 pages

Gene Expression and Osmoregulation in Bacteria

ByHarry H. Yim, Merna R. Villarejo

chapter Chapter 21|15 pages

Genetic Control of Osmoregulation in Plants

ByDavid Rhodes, Yiannis Samaras

chapter Chapter 22|10 pages

Transcription Factors and Stress Proteins in Renal Epithelial Cell Adaptation to Hyperosmotic Stress

ByDavid M. Cohen, Steven R. Gullans

chapter Chapter 23|9 pages

Aldose Reductase Gene Expression and Osmoregulation in Mammalian Renal Cells

ByArlyn García-Pérez, Joan D. Ferraris

chapter Chapter 24|12 pages

Molecular Regulation of Mammalian Osmolyte Transporters

ByH. Moo Kwon