Intravoxel incoherent motion (IVIM) refers to translational movements which within a given voxel and during the measurement time present a distribution of speeds in orientation and/or amplitude. The concept was introduced in 1986 together with the foundation of diffusion MRI because it had been realized that flow of blood in capillaries (perfusion) would mimic a diffusion process and impact diffusion MRI measurements. IVIM-based perfusion MRI, which does not require injection of any tracer or contrast agent, has been first investigated in the brain, but is now experiencing a remarkable revival for applications throughout the body, especially for oncologic applications, from diagnosis to treatment monitoring. 

This book addresses a number of highly topical aspects of the field from leading authorities, introducing the concepts behind IVIM MRI, outlining related methodological issues, and summarizing its current usage and potential for clinical applications. It also presents future research directions, both in terms of methodological development and clinical application fields, extending to new, non-perfusion applications of IVIM MRI, such as virtual MR elastography.

part 1|2 pages

Section I Introduction to IVIM MRI

chapter 1|27 pages

Introduction to IVIM MRI

part 2|2 pages

Section II Other MRI Approaches to Perfusion Imaging

part 4|2 pages

Section III Clinical Applications of IVIM MRI Part 2: Body IVIM MRI

chapter 7|26 pages

Head and Neck IVIM MRI

chapter 8|22 pages

IVIM MRI of the Breast

chapter 9|10 pages

Cardiac IVIM MRI

chapter 10|14 pages

Liver Fibrosis

part 5|2 pages

Section IV Next Frontiers of IVIM MRI