Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems.

This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized.

This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.

chapter 1|14 pages

Cell Disruption

BySubbarayalu Ramalakshmi

chapter 2|11 pages


ByXing Hu, Peng Zhang

chapter 3|28 pages


ByShir Reen Chia, Winn Sen Lam, Wei Hon Seah, Pau Loke Show

chapter 4|22 pages

Membrane-Based Separation Processes

ByKit Wayne Chew, Bervyn Qin Chyuan Tan, Jiang Chier Bong, Kevin Qi Chong Hwang, Pau Loke Show

chapter 5|25 pages

Reverse Osmosis

ByKai Ling Yu, Sho Yin Chew, Shuk Yin Lu, Yoong Xin Pang, Pau Loke Show

chapter 6|40 pages


ByKirupa Sankar Muthuvelu, Senthil Kumar Arumugasamy

chapter 7|22 pages


ByBillie Yan Zhang Hiew, Lai Yee Lee, Suchithra Thangalazhy-Gopakumar, Suyin Gan

chapter 8|23 pages

Liquid-Liquid Separation

ByHui Yi Leong, Pau Loke Show, K. Vogisha Kunjunee, Qi Wye Neoh, Payal Sunil Thadani

chapter 9|19 pages


ByChung Hong Tan, Zahra Motavasel, Navin Raj Vijiaretnam, Pau Loke Show