ABSTRACT

Nanoparticles, products of nanotechnology, are of increasing interest to the pharmaceutical community. They can increase drug solubility, enhance bioavailability, allow tissue targeting, offer decreased side-effects, and improve therapeutic efficacy. Presenting the most pertinent and practical issues in the manufacturing and biological application

chapter 1|20 pages

Fundamentals of Drug Nanoparticles

ByRam B. Gupta

chapter 2|32 pages

Manufacturing of Nanoparticles by Milling and Homogenization Techniques

ByRainer H. Mu€ller, Jan Mo€schwitzer, and Faris Nadiem Bushrab

chapter 3|32 pages

Supercritical Fluid Technology for Particle Engineering

ByRam B. Gupta

chapter 4|18 pages

Polymer or Protein Stabilized Nanoparticles from Emulsions

ByRam B. Gupta

chapter 5|36 pages

Physical Characterization of Nanoparticles

ByRoy J. Haskell

chapter 6|22 pages

Nanoparticle Interface: An Important Determinant in Nanoparticle-Mediated Drug/Gene Delivery

BySanjeeb K. Sahoo, Vinod Labhasetwar

chapter 7|38 pages

Toxicological Characterization of Engineered Nanoparticles

ByPaul J. A. Borm, Roel P. F. Schins

chapter 8|32 pages

Injectable Nanoparticles for Efficient Drug Delivery

ByBarrett Rabinow, Mahesh V. Chaubal

chapter 9|42 pages

Polymeric Nanoparticles for Oral Drug Delivery

ByVivekanand Bhardwaj and Majeti Naga Venkata Ravi Kumar

chapter 10|46 pages

Brain Delivery by Nanoparticles

BySvetlana Gelperina

chapter 11|42 pages

Nanoparticles for Ocular Drug Delivery

ByAniruddha C. Amrite, Uday B. Kompella

chapter 12|20 pages

DNA Nanoparticle Gene Delivery Systems

ByMoses O. Oyewumi, Kevin G. Rice

chapter 13|16 pages

Nanotechnology and Nanoparticles: Clinical, Ethical, and Regulatory Issues

ByMakena Hammond, Uday B. Kompella