Nanomedicine has emerged as a novel field in medicine integrating nano-scale technologies with materials sciences, chemistry and biology. The medical application of nanotechnology has the potential to revolutionize diagnosis and therapy and bring this new field from a notion into reality while impacting the lives of millions around the world. This second edition compiles and details the latest cutting-edge research in science and medicine from the interdisciplinary standpoint who are currently revolutionizing drug delivery techniques through the development of nanomedicines. Edited by Dan Peer, a prominent bio-nanotechnologiest, this book will attract anyone involved materials sciences, chemistry, biology and medicine that would like to design applications in the medical field of nanotechnology towards cancer therapy, inflammation, viral infection, imaging and toxicity.

chapter Chapter 1|21 pages

Biomaterial-Based Particulate Drug Carriers

ByRimona Margalit

chapter Chapter 2|24 pages

Single-Chain Polymer Nanoparticles for Application in Nanomedicine

ByIbon Odriozola, Miren Karmele Aiertza, Germán Cabañero, Hans-Jürgen Grande, Iraida Loinaz

chapter Chapter 3|35 pages

Polyethylene Glycol Polyester Block Copolymers: Biocompatible Carriers for Nanoparticulate Drug Delivery

ByDavid S. Hart, Yunqi Zhao, M. Laird Forrest

chapter Chapter 4|59 pages

Recent Progress in Polymer Therapeutics as Nanomedicines

BySahar Israeli Dangoor, Shani Koshrovski Michael, Hemda Baabur-Cohen, Liora Omer, Ronit Satchi-Fainaro

chapter Chapter 5|42 pages

Polysaccharides as Nanomaterials for Therapeutics

ByShoshy Mizrahy, Dan Peer

chapter Chapter 6|37 pages

RNAi as New Class of Nanomedicines

ByMonika Dominska, Derek M. Dykxhoorn

chapter Chapter 7|42 pages

Novel RNA Interference (RNAi)-Based Nanomedicines for Treating Viral Infections

ByNyree Maes, Skye Zeller, Priti Kumar

chapter Chapter 8|20 pages

Detection and Description of Tissue Disease: Advances in the Use of Nanomedicine for Medical Imaging

ByJason L. J. Dearling, Alan B. Packard

chapter Chapter 9|21 pages

Image-Based High-Content Analysis, Stem Cells and Nanomedicines: A Novel Strategy for Drug Discovery

ByLeonardo J. Solmesky, Yonatan Adalist, Miguel Weil

chapter Chapter 11|27 pages

Complement Activation, Immunogenicity, and Immune Suppression as Potential Side Effects of Liposomes

ByJanos Szebeni, Yechezkel (Chezy) Barenholz

chapter Chapter 12|18 pages

Biomolecular Assemblies as Multifunctional Drug Designs

ByKenneth A. Howard

chapter Chapter 13|44 pages

Rational Design of Polymeric Nanoconstructs for Drug Delivery and Biomedical Imaging

ByAnna Lisa Palange, Miguel Ferreira, Daniele Di Mascolo, Roberto Palomba, Pietro Lenarda, Alexander Cook, Paolo Decuzzi

chapter Chapter 14|37 pages

Barriers in the Tumor Microenvironment to Nanoparticle Activity

ByHanan Abumanhal-Masarweh, Lilach Koren, Omer Adir, Maya Kaduri, Maria Poley, Gal Chen, Aviram Avital, Noga Sharf Pauker, Yelena Mumblat, Jeny Shklover, Janna Shainsky-Roitman, Avi Schroeder

chapter Chapter 15|66 pages

Doxil® — The First FDA-Approved Nano-Drug: From an Idea to a Product

ByYechezkel (Chezy) Barenholz