This book explores the important role of the interferons in infections due to nonviral intracellular pathogens. It deals with the induction of interferons by a variety of intracellular microorganisms and the effects of interferons on the host cells and the microorganisms.

part Part I|49 pages

The Interferon System

chapter 1|24 pages

Interferons and Their Induction

ByJoseph M. Carlin, Ernest C. Borden

chapter 2|23 pages

Interferons and Their Mechanisms of Action

ByDonna M. Paulnock

part Part II|183 pages

Obligate Intracellular Pathogens

chapter 3|20 pages

Interferons, Immunity, and Chlamydiae

ByGerald I. Byrne

chapter 6|13 pages

IFNγ as an Effector Molecule in Antirickettsial Immunity

ByThomas R. Jerrells

chapter 7|18 pages


ByCarolyn M. Black, Jack S. Remington, Robert E. McCabe

chapter 8|18 pages

Toxoplasma gondii

ByE. R. Pfefferkorn

chapter 9|25 pages


ByCarol A. Nacy, Miodrag Belosevic, Monte S. Meltzer, David L. Hoover

chapter 10|9 pages

Modulatory Effects of Interferons on Trypanosoma cruzi Infections

ByGerald Sonnenfeld, Felipe Kierszenbaum

chapter 11|13 pages

Enhancement of Resistance to Trypanosoma cruzi Infection by Recombinant IFNγ

ByRobert E. McCabe, Jack S. Remington, Fausto G. Araujo

chapter 12|17 pages

Antimalarial Activity of IFNγ: Requirement for Immunity to Sporozoite Challenge

ByLouis Schofield, Arturo Ferreira

part Part III|76 pages

Facultative Intracellular Pathogens

chapter 14|24 pages

Role of Interferon in Immunity to Mycobacteria

ByPeter W. Andrew, Douglas B. Lowrie

chapter 15|8 pages

Legionella pneumophila

ByMarcus A. Horwitz

chapter 16|16 pages

Interferon Effects on Infection with Enteroinvasive Bacteria

ByMiklos Degré, Geir Bukholm