ABSTRACT

“Chronic Obstructive Pulmonary Disease is, in 2024, one of the three main causes of death in the world, affecting around 12% of the world population and its incidence is estimated to increase in the coming decades due to continuous exposure to risk factors and to aging. population.

Pulmonary emphysema is one of its most serious phenotypes, with chronic and inexorable progression and, in the most severe stages, it is highly disabling and lethal.

This book reviews knowledge about the pathophysiology of severe pulmonary emphysema and current innovative interventional and minimally invasive therapeutic concepts for the management of these advanced stages of emphysema, based on the best scientific evidence.

This guide provides, to multidisciplinary pulmonary boards of experts in advanced lung diseases, current criteria for the choice of precision therapeutic options, beyond to maintaining optimized medical treatment to control lung hyperinflation and alleviate patients' symptoms.

This book is a valuable resource for clinicians dealing with critically ill patients with COPD.”

1. Pathophysiology of Emphysema, 2. Pulmonary Functional Evaluation for Safe Performance of BLVR, 3 The concept of lung volume reduction and the best evidence, 4. Surgical Concept and Technique of Lung Volume Reduction Surgery, 5. Image Analysis to Identify Target Areas for Lung Volume Reduction, 6. Nuclear Medicine Techniques in Pre-evaluation of Single Pulmonary Nodule Resection, Lung Volume Reduction Surgery and Pre and Post Bronchoscopic Lung Volume Reduction, 7. The Precision Treatment for Severe Lung Emphysema and the Impact of the Multidisciplinary Lung Board, 8. The Current Optimized Medical Treatment and the Impact on Dynamic Hyperinflation, 9. Lung Volume Reduction Surgery: Technique, Tips and Challenges Andrew Akcelik and Charles T. Bakhos, 10. Extending Candidacy for Lung Volume Reduction Surgery, 11. The Interface Lung Emphysema and Lung Cancer, 12. Bronchoscopic Lung Volume Reduction Innovations, 13. Peri-Interventional Clinical Management of Endoscopic Emphysema Treatment, 14. Bronchoscopic Lung Volume Reduction with One-Way Valves: Prevention and Management of Complications, 15. Pulmonary Rehabilitation for COPD Patients, 16. Results and Long-Term Follow Up of Interventional Treatments for Lung Emphysema: Quality of Life Considerations; 17. The Future of Treating Hyperinflation in Emphysema.