ABSTRACT

This book is the first in a series compiling highly cited articles in nanomedicine recently. The series is edited by Lajos P. Balogh, a prominent nanotechnology researcher and journal editor. The first book content is about nanotechnology in cancer research. It also includes a wide variety of must-know topics that will appeal to any researcher involved in nanomedicine, macromolecular science, cancer therapy, and drug delivery research. These 31 articles collected here have already acquired more than 3500 citations (i.e., over a hundred on average), highlighting the importance and recognized professional interest of the scientists working in this field.

chapter 2|25 pages

Nanostructure-Mediated Drug Delivery

ByGareth A. Hughes

chapter 3|52 pages

Nanoparticles: A Boon to Drug Delivery, Therapeutics, Diagnostics and Imaging

BySuphiya Parveen, Ranjita Misra, Sanjeeb K. Sahoo

chapter 4|29 pages

Emerging Nanopharmaceuticals

ByDhruba J. Bharali, Willie E. Bawarski, Elena Chidlowsky, Shaker A. Mousa

chapter 5|30 pages

Significance of Synthetic Nanostructures in Dictating Cellular Response

ByEvelyn K. F. Yim, Kam W. Leong

chapter 6|11 pages

Electrospun Bioscaffolds That Mimic the Topology of Extracellular Matrix

ByDong Han, Pelagia-Irene Gouma

chapter 7|44 pages

Preparation of Drug-Loaded Polymeric Nanoparticles

ByCatarina Pinto Reis, Ronald J. Neufeld, Francisco Veiga, Antonio J. Ribeiro

chapter 8|20 pages

In vivo Tumor Suppression Efficacy of Mesoporous Silica Nanoparticle-Based Drug Delivery System: Enhanced Efficacy by Folate Modification

ByCatarina Pinto Reis, Zongxi Li, Jeffrey I. Zink, Fuyuhiko Tamanoi

chapter 9|29 pages

Update on Nanoparticle-Mediated Immune Mechanisms for Dendritic Cell-Based Targeted Immunity and Cancer

BySoledad Lopez, Rebecca Klippstein, David Pozo

chapter 10|31 pages

Curcumin-Loaded γ-Cyclodextrin Liposomal Nanoparticles as Delivery Vehicles for Osteosarcoma

BySantosh S. Dhule, Patrice Penfornis, Trivia Frazier, Ryan Walker, Joshua Feldman, Grace Tan, Jibao Hec, Alina Alb, Vijay John, Radhika Pochampally

chapter 11|20 pages

Influence of Purity and Surface Oxidation on Cytotoxicity of Multiwalled Carbon Nanotubes with Human Neuroblastoma Cells

ByOrazio Vittorio, Vittoria Raffa, Alfred Cuschieri

chapter 12|29 pages

Hollow Chitosan-Alginate Multilayer Microcapsules as Drug Delivery Vehicle: Doxorubicin Loading and in vitro and in vivo Studies

ByQinghe Zhao, Baosan Han, Zhaohai Wang, Changyou Gao, Chenghong Peng, Jiacong Shen

chapter 13|22 pages

ZnO Nanorod-Induced Apoptosis in Human Alveolar Adenocarcinoma Cells via p53, Survivin and bax/bcl-2 Pathways: Role of Oxidative Stress

ByMaqusood Ahamed, Mohd Javed Akhtar, Mohan Raja, Iqbal Ahmad, Mohammad Kaleem Javed Siddiqui, Mohamad S. AlSalhi, Salman A. Alrokayan

chapter 14|20 pages

Camptothecin in Sterically Stabilized Phospholipid Micelles: A Novel Nanomedicine

ByOtilia M. Koo, Israel Rubinstein, Hayat Onyuksel

chapter 15|22 pages

Photoablation of Glioblastoma Stem Cells by Single-Walled Carbon Nanotubes Functionalized with CD133 Antibody

ByChung-Hao Wang, Shih-Hwa Chiou, Chen-Pin Chou, Yu-Chih Chen, Yao-Jhang Huang, Ching-An Peng

chapter 16|29 pages

Surface chemistry influences cancer killing effect of TiO2 nanoparticles

ByPaul Thevenot, Jai Cho, Dattatray Wavhal, Ashwin Nair, Richard B. Timmons, Liping Tang

chapter 17|20 pages

Endocytosis of titanium dioxide nanoparticles in prostate cancer PC-3M cells

ByKenneth T. Thurn, Hans Arora, Tatjana Paunesku, Aiguo Wu, Eric M. B. Brown, Caroline Doty, Jeff Kremer, Gayle Woloschak

chapter 18|25 pages

Multi-Walled Carbon Nanotube Exposure Alters Protein Expression in Human Keratinocytes

ByFrank A. Witzmann, Nancy A. Monteiro-Riviere

chapter 20|26 pages

Carbon Nanotubes as Functional Excipients for Nanomedicines: II. Pharmaceutical Properties

ByMarianna Foldvari, Mukasa Bagonluri

chapter 21|18 pages

Fluorescence Intensity and Lifetime Imaging of Free and Micellar-Encapsulated Doxorubicin in Living Cells

ByXiaowen Dai, Zhilian Yue, Mark E. Eccleston, Swartling Johannes, Nigel K.H. Slater, Clemens F. Kaminski

chapter 22|7 pages

Doxorubicin-Loaded Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Cancer Therapy

ByKeon Wook Kang, Myung-Kwan Chun, Ok Kim, Robhash Kusam Subedi, Sang-Gun Ahn, Jung-Hoon Yoon, Hoo-Kyun Choi

chapter 23|22 pages

PEGylated PLGA Nanoparticles for the Improved Delivery of Doxorubicin

ByJason Park, Peter M. Fong, Jing Lu, Kerry S. Russell, Carmen J. Booth, W. Mark Saltzman, Tarek M. Fahmy

chapter 24|25 pages

Gold-Doxorubicin Nanoconjugates for Overcoming Multidrug Resistance

ByJinping Cheng, Yan-Juan Gu, Cornelia Wing-Yin Man, Wing-Tak Wong, Shuk Han Cheng

chapter 25|23 pages

In vitro Evaluation of Novel Polymer-Coated Magnetic Nanoparticles for Controlled Drug Delivery

ByMaham Rahimi, Aniket Wadajkar, Khaushik Subramanian, Monet Yousef, Weina Cui, Jer-Tsong Hsieh, Kytai Truong Nguyen

chapter 26|20 pages

Targeting of Albumin-Embedded Paclitaxel Nanoparticles to Tumors

ByPriya Prakash Karmali, Venkata Ramana Kotamraju, Mark Kastantin, Matthew Black, Dimitris Missirlis, Matthew Tirrell, Erkki Ruoslahti

chapter 28|25 pages

Beta-Casein Nanovehicles for Oral Delivery of Chemotherapeutic Drugs

ByAlina Shapira, Yehuda G. Assaraf, Yoav D. Livney

chapter 29|23 pages

Classification of Lung Cancer Histology by Gold Nanoparticle Sensors

ByOrna Barash, Nir Peled, Ulrike Tisch, Paul A. Bunn, Fred R. Hirsch, Hossam Haick

chapter 30|16 pages

Enhancement of Radiation Effects by Gold Nanoparticles for Superficial Radiation Therapy

ByWan Nordiana Rahman, Nour Bishara, Trevor Ackerly, Cheng Fa He, Price Jackson, Christopher Wong, Robert Davidson, Moshi Geso

chapter 31|22 pages

Radioactive Gold Nanoparticles in Cancer Therapy: Therapeutic Efficacy Studies of GA-198AuNP Nanoconstruct in Prostate Tumor-Bearing Mice

ByNripen Chanda, Para Kan, Lisa D. Watkinson, Ravi Shukla, Ajit Zambre, Terry L. Carmack, Hendrik Engelbrecht, John R. Lever, Kavita Katti, Genevieve M Fent, Stan W. Casteel, C. Jeffrey Smith, William H. Miller, Silvia Jurisson, Evan Boote, J.David Robertson, Cathy Cutler, Marina Dobrovolskaia, Raghuraman Kannan, Kattesh V. Katti

chapter 32|32 pages

The present and future of nanotechnology in human health care

ByS. K. Sahoo, S. Parveen, J. J. Panda