Psoriasis is a life-long chronic autoimmune disease characterized by thick scaly skin lesions and often associated with severe arthritis. In psoriasis, lesions skin cells, keratinocytes, grow too quickly, resulting in thick, white, silvery or red patches on skin. Normal skin cells grow gradually and flake off about every four weeks, but psoriasis causes new skin cells to move rapidly to the surface of the skin in days rather than weeks. Psoriasis symptoms often appear on the elbows, scalp, feet, knees, hands, or lower back, or as flaking or patches on the skin. It is most common in adults, but teenagers and children can also suffer from psoriasis.

Psoriasis is not only a skin condition; it is a chronic disease of the immune system. Chronic psoriasis is associated with other health conditions such as psoriatic arthritis, several inflammatory disorders, type 2 diabetes, and cardiovascular disease. This book provides extensive coverage of psoriasis and psoriatic arthritis. It features information on epidemiology and etiology of psoriasis, pathogenesis, genetics of psoriasis, clinical manifestations, and treatment options using cutting-edge drugs including adalimumab and tofacitinib.

Natural phytochemicals and nutraceuticals have demonstrated efficacy in ameliorating psoriasis. The book dedicates comprehensive coverage of nutraceutical therapeutic options including antioxidants, bioactive peptides, carotenoids, alpha lipoic acid, curcumin, and whey protein. These inexpensive natural therapeutics are not associated with any known adverse side effects.


section I|2 pages

Disease Epidemiology and Genetics

chapter 1|6 pages

Epidemiology of Psoriasis and Psoriatic Arthritis

ByM. B. Adarsh, Aman Sharma

chapter 2|24 pages

Genetics of Psoriasis and Psoriatic Arthritis

ByRemy Pollock, Vinod Chandran

section II|2 pages


chapter 3|10 pages

Inflammation in Psoriasis and Psoriatic Arthritis

ByLatika Gupta, Amita Aggarwal

chapter 4|8 pages

Psoriasis and Diabetes: An Unholy Alliance

BySatinath Mukhopadhyay, Deep Dutta, Dipyaman Ganguly

chapter 5|70 pages

Angiogenesis and Roles of Adhesion Molecules in Psoriatic Disease

ByAsmita Hazra, Saptarshi Mandal

chapter 6|10 pages

Multifaceted Role of Th17 Cells in Psoriatic Disease

BySoumya D. Chakravarty

chapter 7|14 pages

Nerve Growth Factor and Its Receptor System in Rheumatologic Diseases and Pain Management

A New Dimension in Pathogenesis and Novel Drugs in the Pipeline
BySmriti K. Raychaudhuri, Siba P. Raychaudhuri

section III|2 pages

Psoriatic Disease: Clinical Profiles

chapter 8|10 pages

Psoriasis: Clinical Spectrum

ByChelsea Ma, Smriti K. Raychaudhuri, Emanual Maverakis, Siba P. Raychaudhuri

chapter 9|6 pages

Clinical Spectrum of Spondyloarthritis

ByJoerg Ermann

chapter 10|10 pages

Comorbidities in Psoriatic Arthritis

ByMaria J. Antonelli, Marina Magrey

section IV-A|2 pages

Treatment Regimen

chapter 11|18 pages

Current Recommendations for the Treatment of Psoriasis

ByChelsea Ma, Emanual Maverakis

chapter 12|28 pages

Management of Psoriatic Arthritis

BySiba P. Raychaudhuri, Reason Wilken, Debashis Sarkar, Emanual Maverakis, Smriti K. Raychaudhuri

chapter 13|12 pages

Targeting IL-23/IL-17 Axis for Treatment of Psoriasis and Psoriatic Arthritis

BySubhashis Banerjee, Philip Mease

chapter 14|8 pages

DMARD Treatment in Patients with Psoriatic Arthritis

ByRafael Valle Oñate, Andrea Chaparro

chapter 15|18 pages

Topical Therapies for Psoriasis

ByMichael Sticherling

chapter 16|10 pages

Overview of JAK-STAT Pathways in Spondyloarthritis

BySmriti K. Raychaudhuri, Sanchita Raychaudhuri, Debasis Bagchi, Anand Swaroop, Siba P. Raychaudhuri

chapter 17|10 pages

Concept of Total Care

Multidisciplinary Approach for the Management of Psoriatic Disease
BySmriti K. Raychaudhuri, Debasis Bagchi, Siba P. Raychaudhuri

section IV-B|2 pages

Treatment Regimen

chapter 18|16 pages

Nutraceutical Components in the Treatment of Psoriasis and Psoriatic Arthritis

ByUrmila Jarouliya, Raj K. Keservani

chapter 19|24 pages

Herbal Products for the Treatment of Psoriasis

ByAnna Herman, Andrzej P. Herman

chapter 20|12 pages

Impact of Nutrition and Dietary Supplementation on Psoriasis Pathology

ByOdete Mendes, Mithila Shitut, Jayson Chen