ABSTRACT

Much of the biology of oxidative stress and oxidative signalling centres on the generation and handling of hydrogen peroxide. The overall aim for this book would be to provide an insightful and useful forum to assist with the understanding of the relevance of hydrogen peroxide generation and how this is managed in human biology. The target audience would be those who currently have an interest in the generation of ROS, but who do not have expertise in chemistry, as well as those experts in the chemistry of oxidative stress, but without detailed understanding of the biologically relevant setting. We would aim to bridge the gap in understanding between chemistry and biology.

section I|145 pages

Chemistry and Biochemistry of H2O2

chapter 1|14 pages

Hydrogen Peroxide, a Molecule with a Janus Face

Its History, Chemistry, and Biology

section II|131 pages

Biological Sources of H2O2

section III|72 pages

Myeloperoxidase and Derived Oxidants

section IV|98 pages

H2O2 in Cellular Metabolism and Signaling

chapter 14|11 pages

Hydrogen Peroxide-Dependent Redox Signaling

Basic Concepts and Unanswered Questions