ABSTRACT

Key features:

  • Serves as the detailed, authoritative source of the clinical chemistry of the most commonly used laboratory animals
  • Includes detailed chapters dedicated to descriptions of clinical chemistry-related topics specific to each laboratory species as well as organ/class-specific chapters
  • Presents information regarding evaluation and interpretation of a variety of individual clinical chemistry end points
  • Concludes with detailed chapters dedicated to descriptions of statistical analyses and biomarker development of clinical chemistry-related topics
  • Provides extensive reference lists at the end of each chapter to facilitate further study
  •  

    Extensively updated and expanded since the publication of Walter F. Loeb and Fred W. Quimby’s second edition in 1999, the new The Clinical Chemistry of Laboratory Animals, Third Edition continues as the most comprehensive reference on in vivo animal studies. By organizing the book into species- and organ/class-specific chapters, this book provides information to enable a conceptual understanding of clinical chemistry across laboratory species as well as information on evaluation and interpretation of clinical chemistry data relevant to specific organ systems.

    Now sponsored by the American College of Laboratory Animal Medicine (ACLAM), this well-respected resource includes chapters on multiple laboratory species and provides pertinent information on their unique physiological characteristics, methods for sample collection, and preanalytical sources of variation for the particular species. Basic methodology for common procedures for each species is also discussed.

    New Chapters in the Third Edition Include:

    • The Laboratory Zebrafish and Other Fishes
    • Evaluation of Cardiovascular and Pulmonary Function and Injury
    • Evaluation of Skeletal Muscle Function and Injury
    • Evaluation of Bone Function and Injury
    • Vitamins
    • Development of Biomarkers
    • Statistical Methods

    The Clinical Chemistry of Laboratory Animals, Third Edition is intended as a reference for use by veterinary students, clinical veterinarians, verterinary toxicologists, veterinary clinical pathologists, and laboratory animal veterinarians to aid in study design, collection of samples, and interpretation of clinical chemistry data for laboratory species.

    chapter 1|32 pages

    The Laboratory Mouse

    ByRichard H. Luong

    chapter 2|46 pages

    The Laboratory Rat

    ByNancy E. Everds, Lila Ramaiah

    chapter 3|34 pages

    The Laboratory Rabbit

    ByAnna Hampton, Tara Cotroneo, Lesley A. Colby

    chapter 4|40 pages

    The Laboratory Dog

    ByJulia Whitaker, Allison R. Rogala, Dana N. LeVine, Craig A. Fletcher

    chapter 5|58 pages

    The Laboratory Pig

    ByAlain Stricker-Krongrad, Larry D. Brown, Guy F. Bouchard, M. Michael Swindle, Stan W. Casteel

    chapter 6|78 pages

    The Nonhuman Primate

    ByKirstin F. Barnhart

    chapter 7|16 pages

    The Laboratory Hamster

    ByCharles B. Clifford, Joe H. Simmons

    chapter 8|26 pages

    The Laboratory Guinea Pig

    ByPatrick Sharp

    chapter 9|14 pages

    The Laboratory Ferret

    ByMary M. Patterson, James G. Fox

    chapter 10|22 pages

    The Laboratory Zebrafish and Other Fishes

    ByClaudia Harper

    chapter 11|40 pages

    Evaluation of Hepatic Function and Injury

    ByCharles E. Wiedmeyer

    chapter 12|38 pages

    Evaluation of Renal Function and Injury

    ByDenise Bounous, Ernie Harpur

    chapter 13|30 pages

    Evaluation of Cardiovascular and Pulmonary Function and Injury

    ByPeter O'Brien

    chapter 14|40 pages

    Evaluation of Skeletal Muscle Function and Injury

    ByCarol B. Grindem, Jennifer A. Neel, Carolina Escobar

    chapter 15|36 pages

    Evaluation of Bone Function and Injury

    ByHolly L. Jordan, Bruce E. LeRoy

    chapter 16|36 pages

    Biochemistry of Immunoglobulins

    ByBarbara R. von Beust, Gregory S. Travlos

    chapter 17|58 pages

    Complement

    ByBarbara R. von Beust, Gregory S. Travlos

    chapter 18|32 pages

    Transport Proteins

    ByClaire L. Parry

    chapter 19|68 pages

    Acute Phase Proteins

    ByClaire L. Parry

    chapter 20|32 pages

    Carbohydrate Metabolism

    ByOwen P. McGuinness, Masakasu Shiota

    chapter 21|96 pages

    Lipids

    ByDana Walker, Lindsay Tomlinson

    chapter 22|66 pages

    Electrolytes, Blood Gases, and Acid–Base Balance

    ByIsabel A. Lea, Susan J. Borghoff, Gregory S. Travlos

    chapter 23|68 pages

    Hormones

    ByJerome M. Goldman, Lori K. Davis, Ralph L. Cooper

    chapter 24|86 pages

    Vitamins, Selected Diet-Derived Factors, and Minerals

    ByRobert B. Rucker, Andrea J. Fascetti, Jennifer A. Larsen

    chapter 25|12 pages

    Development of Biomarkers

    ByHolly L. Jordan

    chapter 26|16 pages

    Statistical Methods

    ByGrace E. Kissling