ABSTRACT

Offering the latest information in magnetic nanoparticle (MNP) research, this book builds upon the success of the first volume and provides an updated and comprehensive review, from synthesis, characterization, and biofunctionalization to clinical applications of MNPs, including the diagnosis and treatment of cancers. The book captures some of emerging research area which was not available in the first volume. Good Manufacturing Practices and Commercialization of MNPs are also included. This volume, also written by some of the most qualified experts in the field, incorporates new developments in the literature, and continues to bridge the gaps between the different areas in this field.

section I|2 pages

Fabrication, Characterisation of MNPs

chapter 1|22 pages

Controlling the Size and Shape of Uniform Magnetic Iron Oxide Nanoparticles for Biomedical Applications

ByHelena Gavilán, Maria Eugênia Fortes Brollo, Lucía Gutiérrez, Sabino Veintemillas-Verdaguer, María del Puerto Morales

chapter 2|18 pages

Magnetic Nanochains

Properties, Syntheses and Prospects
ByIrena Markovic-Milosevic, Vincent Russier, Marie-Louise Saboungi, Laurence Motte

chapter 3|10 pages

Carbon-Coated Magnetic Metal Nanoparticles for Clinical Applications

ByMartin Zeltner, Robert N. Grass

chapter 4|22 pages

Bioinspired Magnetic Nanoparticles for Biomedical Applications

ByChangqian Cao, Yongxin Pan

section II|2 pages

Biofunctionalisation of MNPs

chapter 5|20 pages

Main Challenges about Surface Biofunctionalization for the In Vivo Targeting of Magnetic Nanoparticles

ByLaurent Adumeau, Marie-Hélène Delville, Stéphane Mornet

chapter 6|25 pages

Experimental Considerations for Scalable Magnetic Nanoparticle Synthesis and Surface Functionalization for Clinical Applications

ByAlec P. LaGrow, Maximilian O. Besenhard, Roxanne Hachani, Nguyễn T. K. Thanh

chapter 7|18 pages

Magnetic Polymersomes for MRI and Theranostic Applications

ByAdeline Hannecart, Dimitri Stanicki, Luce Vander Elst, Robert N. Muller, Sophie Laurent

chapter 8|22 pages

Ultrasmall Iron Oxide Nanoparticles Stabilized with Multidentate Polymers for Applications in MRI

ByJung Kwon (John) Oh, Marc-André Fortin

chapter 9|13 pages

Encapsulation and Release of Drugs from Magnetic Silica Nanocomposites

ByDamien Mertz, Sylvie Bégin-Colin

section III|2 pages

In-Vitro Application of MNPs

chapter 10|26 pages

Current Progress in Magnetic Separation-Aided Biomedical Diagnosis Technology

BySim Siong Leong, Swee Pin Yeap, Siew Chun Low, Rohimah Mohamud, JitKang Lim

chapter 11|28 pages

Magnetic Separation in Integrated Micro-Analytical Systems

ByKazunori Hoshino

chapter 12|18 pages

Magnetic Nanoparticles for Organelle Separation

ByMari Takahashi, Shinya Maenosono

chapter 13|24 pages

Magnetic Nanoparticle-Based Biosensing

ByKai Wu, Diqing Su, Yinglong Feng, Jian-Ping Wang

section IV|2 pages

In-Vivo Application of MNPs

chapter 14|16 pages

Immunotoxicity and Safety Considerations for Iron Oxide Nanoparticles

ByGary Hannon, Melissa Anne Tutty, Adriele Prina-Mello

chapter 15|16 pages

Impact of Core and Functionalized Magnetic Nanoparticles on Human Health

ByBella B. Manshian, Uwe Himmelreich, Stefaan J. Soenen

chapter 16|14 pages

Magnetic Nanoparticles for Cancer Treatment Using Magnetic Hyperthermia

ByLaura Asín, Grazyna Stepien, María Moros, Raluca Maria Fratila, Jesús Martínez de la Fuente

chapter 17|12 pages

Nanoparticles for Nanorobotic Agents Dedicated to Cancer Therapy

ByMahmood Mohammadi, Charles Tremblay, Ning Li, Kévin Gagné, Maxime Latulippe, Maryam S. Tabatabaei, Sylvain Martel

chapter 18|12 pages

Smart Nanoparticles and the Effects in Magnetic Hyperthermia In Vivo

ByIngrid Hilger

chapter 19|22 pages

Noninvasive Guidance Scheme of Magnetic Nanoparticles for Drug Delivery in Alzheimer’s Disease

ByAli Kafash Hoshiar, Tuan Anh Lea, Faiz Ul Amin, Xingming Zhang, Myeong Ok Kim, Jungwon Yoon

chapter 20|16 pages

Design, Fabrication and Characterization of Magnetic Porous PDMS as an On-Demand Drug Delivery Device

ByAli Shademani, Hongbin Zhang, Mu Chiao

chapter 21|14 pages

Magnetic Particle Transport in Complex Media

ByLamar O. Mair, Aleksandar N. Nacev, Sagar Chowdhury, Pavel Stepanov, Ryan Hilaman, Sahar Jafari, Benjamin Shapiro, Irving N. Weinberg

chapter 22|16 pages

Magnetic Nanoparticles for Neural Engineering

ByGerardo F. Goya, Vittoria Raffa

chapter 23|20 pages

Radionuclide Labeling and Imaging of Magnetic Nanoparticles

ByBenjamin P. Burke, Christopher Cawthorne, Stephen J. Archibald

chapter 25|22 pages

Stimuli-Regulated Cancer Theranostics Based on Magnetic Nanoparticles

ByYanmin Ju, Shiyan Tong, Yanglong Hou

section V|2 pages

Good Manufacturing Practice

chapter 26|10 pages

Good Manufacturing Practices (GMP) of Magnetic Nanoparticles

ByNazende Günday Türeli, Akif Emre Türeli