The first medical reference textbook to compile an unprecedented synthesis of evidence for regenerative orthopedics by key opinion leaders

Thirty-five authors address your clinical questions

What emerging technologies are right for my clinical practice? How can I strengthen my patients before their orthopedic surgery? Practically speaking, how can I leverage the latest metabolic therapies to safeguard my patients from toxins, medications, food and chronic diseases known to adversely affect the musculoskeletal system?

"Ask the Author" feature

Would you like to discuss a patient with a particular author? Now you can do so at www.betterorthopedics.com.

First to be second

Did you notice this book is the first book in regenerative orthopedics to publish a second edition? This diverse author team leads the growing field of regenerative orthopedics and offers the broadest and in-depth approach to leveraging metabolic therapies.


This book comprises the professional opinion of its authors. It does not claim to represent guidelines, recommendations, or the current standard of medical care.

part Part I|1 pages

Cross-Cutting Technologies

chapter Chapter 1|17 pages

Regenerative Orthopedics Enabled by Cross-Cutting Technologies

ByKenneth Cintron

chapter Chapter 2|17 pages


Genome-Directed Therapies in Orthopedics
ByJoseph R. Veltmann, Roberta L. Kline

chapter Chapter 4|33 pages

Veterinary Medicine’s Advances in Regenerative Orthopedics

BySophie H. Bogers, Jennifer G. Barrett

chapter Chapter 5|19 pages


How Ultrasound Diagnostics Guide Regenerative Orthopedic Therapies to Restore Biomechanical Function
ByBradley D. Fullerton

part Part II|1 pages

Clinical Approaches to Preventing and Treating Metabolic Dysfunction

chapter Chapter 6|26 pages

Photobiomodulation Therapy in Orthopedics

Metabolic Effects
ByMichael R. Hamblin

chapter Chapter 9|7 pages

Periodontal Disease

Treatable, Nutrition-Related, and with Systemic Repercussions
ByDavid Kennedy

chapter Chapter 10|22 pages

Reduction in Orthopedic Conditions through Teledontic Treatment of Pharyngorofacial Disorders

ByJoseph Yousefian, Michael N. Brown

chapter Chapter 11|8 pages

Drug-Related Muscular Pain

BySahar Swidan

chapter Chapter 12|16 pages

Metabolic Interventions for Sarcopenic Obesity

ByLyon Gabrielle, Jamie I. Baum

chapter Chapter 13|11 pages

Drug-Related Sarcopenia

BySahar Swidan

chapter Chapter 14|12 pages

Sex Hormones and Their Impact on Sarcopenia and Osteoporosis

ByPamela W. Smith

chapter Chapter 15|20 pages

Treating the Dysmetabolism Underlying Osteoporosis

ByXaviour Walker, Joseph Lamb

part Part III|1 pages

Metabolic Therapies for Specific Orthopedic Conditions

chapter Chapter 17|25 pages

Perioperative Metabolic Therapies in Orthopedics

ByFrederick T. Sutter

chapter Chapter 18|19 pages

Metabolic Therapies for Muscle Injury

ByAna V. Cintrón, Kenneth Cintron

chapter Chapter 19|10 pages


Addressing the Chronic Pain and Pathophysiology
ByDavid Musnick

chapter Chapter 20|7 pages

Metabolic Therapies in the Management of Heel Pain

ByEmily M. Splichal

chapter Chapter 21|12 pages

Fascial Syndromes

Emerging, Treatable Contributors to Musculoskeletal Pain
ByDavid Lesondak

chapter Chapter 22|19 pages

Metabolic Approaches to the Treatment of Back Pain

ByCarrie Diulus, Patrick Hanaway

chapter Chapter 23|14 pages

Optimizing Metabolism to Treat Fractures and Prevent Nonunion

ByJacob Wilson, Scott Boden, Kenneth Cintron, Mara Schenker

chapter Chapter 25|29 pages


Comprehensive Treatment
ByDavid Musnick, Richard D. Batson

chapter Chapter 26|15 pages

Integrative Approaches to Autoimmune Arthritis

ByGeorge E. Muñoz