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      Handbook of Small Animal Imaging
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      Book

      Handbook of Small Animal Imaging

      DOI link for Handbook of Small Animal Imaging

      Handbook of Small Animal Imaging book

      Preclinical Imaging, Therapy, and Applications

      Handbook of Small Animal Imaging

      DOI link for Handbook of Small Animal Imaging

      Handbook of Small Animal Imaging book

      Preclinical Imaging, Therapy, and Applications
      Edited ByGeorge C. Kagadis, Nancy L. Ford, Dimitrios N. Karnabatidis, George K. Loudos
      Edition 1st Edition
      First Published 2016
      eBook Published 12 December 2018
      Pub. Location Boca Raton
      Imprint CRC Press
      DOI https://doi.org/10.1201/9781315373591
      Pages 624
      eBook ISBN 9781315373591
      Subjects Engineering & Technology, Environment & Agriculture, Medicine, Dentistry, Nursing & Allied Health, Physical Sciences
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      Get Citation

      Kagadis, G.C., Ford, N.L., Karnabatidis, D.N., & Loudos, G.K. (Eds.). (2016). Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications (1st ed.). CRC Press. https://doi.org/10.1201/9781315373591

      ABSTRACT

      The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans.

      Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research.

      The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.

      TABLE OF CONTENTS

      section I|47 pages

      Introduction to Small Animal Imaging, Therapy, and Applications

      chapter 1|3 pages

      Defining Small Animal Imaging, Therapy, and Applications

      ByNancy L. Ford, George K. Loudos, Dimitrios N. Karnabatidis, George C. Kagadis

      chapter 2|10 pages

      Ethics and Regulations for Research with Animals

      ByWilliam R. Hendee

      chapter 3|18 pages

      Small Animal Handling, Care, and Anesthesia

      ByTamara Godbey

      chapter 4|13 pages

      Preclinical Models

      ByIrene Cuadrado, Jesús Egido, Jose Luis Zamorano, Carlos Zaragoza

      section II|69 pages

      Small Animal Imaging Ionizing Radiation

      chapter 5|16 pages

      Microcomputed Tomography

      ByNancy L. Ford

      chapter 6|10 pages

      Digital Subtracted Angiography of Small Animals

      ByStavros Spiliopoulos, George C. Kagadis, Dimitrios N. Karnabatidis, G. Allan Johnson, Cristian Badea

      chapter 7|21 pages

      Single-Photon Emission Computed Tomography

      ByMatthew A. Lewis

      chapter 8|19 pages

      Positron Emission Tomography

      ByVesna Sossi, Matthew Walker

      section III|45 pages

      Small Animal Imaging Nonionizing Radiation

      chapter 9|19 pages

      MR Imaging

      ByDmitri Artemov

      chapter 10|23 pages

      Optical Imaging

      ByMatthew A. Lewis

      section IV|81 pages

      Hybrid Imaging

      chapter 11|20 pages

      Optical-CT Imaging

      ByXueli Chen, Dongmei Chen, Fenglin Liu, Wenxiang Cong, Ge Wang, Jimin Liang

      chapter 12|17 pages

      Pet/Ct

      ByMohammad Reza Ay, Nafiseh Ghazanfari

      chapter 13|28 pages

      Introduction to Combining MRI with PET

      ByVolkmar Schulz, Jakob Wehner, Yannick Berker

      chapter 14|13 pages

      Exotic Imaging Approaches

      ByMaria Koutsoupidou, Irene S. Karanasiou

      section V|80 pages

      Imaging Agents

      chapter 15|28 pages

      X-Ray, MRI, and Ultrasound Agents Basic Principles

      ByMichael F. Tweedle, Krishan Kumar, Michael V. Knopp

      chapter 16|38 pages

      Radiochemistry for Preclinical Imaging Studies

      BySven Macholl, Matthias Glaser

      chapter 17|12 pages

      Molecular Targets and Optical Probes

      ByEleni K. Efthimiadou, George Kordas

      section VI|80 pages

      Therapeutic Research Platforms

      chapter 18|23 pages

      Developing Technologies for Small Animal Radiotherapy

      ByFrank Verhaegen, James Stewart, David Jaffray

      chapter 19|12 pages

      Dosimetry of Ionizing Radiation in Small Animal Imaging

      ByMichael G. Stabin

      chapter 20|20 pages

      Treatment Planning for Small Animals

      ByFrank Verhaegen

      chapter 21|22 pages

      Radiolabeled Agents for Molecular Imaging and/or Therapy

      ByDimitrios Psimadas, Eirini A. Fragogeorgi

      section VII|43 pages

      Image Quantification

      chapter 22|14 pages

      Quantification in Nuclear Preclinical Imaging

      ByIstvan Szanda

      chapter 23|12 pages

      Performance Assessment of Small Animal Imaging Systems and Common Standards

      ByNancy L. Ford

      chapter 24|15 pages

      Monte Carlo Simulations in Imaging and Therapy

      ByPanagiotis Papadimitroulas, George C. Kagadis, George K. Loudos

      section VIII|137 pages

      Applications

      chapter 25|10 pages

      Small Animal Imaging and Therapy

      How They Affect Patient Care
      ByLawrence W. Dobrucki

      chapter 26|24 pages

      Applications for Drug Development

      ByJessica Kalra, Donald T. Yapp, Murray Webb, Marcel B. Bally

      chapter 27|22 pages

      Imaging of Intracellular Targets

      ByVeerle Kersemans

      chapter 28|17 pages

      Imaging of Cell Trafficking and Cell Tissue Homing

      ByVeerle Kersemans

      chapter 29|22 pages

      Imaging of Cardiovascular Disease

      ByAleksandra Kalinowska, Lawrence W. Dobrucki

      chapter 30|19 pages

      Imaging Angiogenesis

      ByLawrence W. Dobrucki

      chapter 31|9 pages

      Imaging of Hypoxia, Apoptosis, and Inflammation

      ByStavros Spiliopoulos, Athanasios Diamantopoulos

      chapter 32|9 pages

      Vessel Wall Imaging

      ByStavros Spiliopoulos
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