This book discusses the topic of affinity electrophoresis (AFF-EP), which has become a useful tool for studies of biomolecular interactions. The book will discuss AFF-EP as an analytical method which has been used successfully for the diagnosis, differentiation, and monitoring of patients with various diseases. The book will also discuss other uses for the AFF-EP method.

part 1|115 pages

Principles and Technical Details of Affinity Electrophoresis (AFF-EP)

section 1|55 pages

Theoretical Background, Principles, and Technical Details of AFF-EP

section 2|28 pages

Varieties of AFF-EP Systems

chapter 3|10 pages

Affinity Isotachophoresis on Porous Membranes

ByDorota Schranz, Stanislaw Morkowski, Garri I. Abelev

section 3|29 pages

Comparison of Results Obtained by AFF-EP and Other Affinity Based Techniques

part 2|63 pages

Application of AFF-EP for Basic Research

chapter 9|19 pages

Regulation of Glycosylation of Acute-Phase Proteins by Cytokines In Vitro

ByAndrzej Mackiewicz, Odette Pos, Marleen van der Stelt, Singh H. Yap, Malgorzata Kapcinska, Maria Łaciak, Michael J. Dewey, Franklin G. Berger, Heinz Baumann, Irving Kushner, Willem van Dijk

chapter 10|8 pages

Capabilities of Peripheral Blood Monocytes to Induce Changes in Glycosylation of Plasma Proteins In Vitro

ByAndrzej Mackiewicz, Magdalena Sobieska, Malgorzata Kapcinska, Tomasz Pawlowski

part 3|90 pages

Clinical Application of AFF-EP

section 1|6 pages

AFF-EP in Management of Neonates and Children

chapter 12|6 pages

Maternal and Newborn Serum Alpha1-Acid Glycoprotein at Delivery: Concentrations and Caie Patterns in the Presence of Concanavalin A

ByNathalie Seta, Danielle Lebrun, Aline de Crépy, Jeanne Féger, Geneviève Durand

section 2|37 pages

Alpha1-Fetoprotein (AFP), Alpha1-Acid Glycoprotein (AGP), Haptoglobin, and Ceruloplasmin Microheterogeneity in Diagnosis, Differentiation, and Management of Cancer Patients

chapter 13|8 pages

Glycoforms of Alpha1-Acid Glycoprotein in Cancer

ByJan Brȩborowicz, Aleksander Gorny, Krzysztof Drews, Andrzej Mackiewicz

section 3|12 pages

Microheterogeneity of Acute-Phase Proteins in Rheumatic Diseases

chapter 16|10 pages

Glycoforms of Alpha1-Acid Glycoprotein in the Management of Rheumatic Patients

ByAndrzej Mackiewicz, Tomasz Pawlowski, Aleksander Gorny, Irving Kushner

section 4|9 pages

Section IV AFF-EP for Assessment of Liver Damage

chapter 17|7 pages

Alterations of Concanavalin a Patterns of Human Alpha1-Acid Glycoprotein in Liver Diseases

ByDurand Geneviève, Seta Nathalie, Jezequel Maryvonne, Fèger Jeanne

section 5|22 pages

AFF-EP in Other Pathological States

chapter 18|5 pages

Microheterogeneity of Orosomucoid and Acute-Phase Reaction in Aids

ByJohn-Erik S. Hansen, Court Pedersen

chapter 19|8 pages

Glycoforms of Serum Alpha1-Acid Glycoprotein in Patients with Mediastinal Infection

ByJeanne Feger, Nathalie Seta, Michelìne Giai-Brueri, Geneviève Durand

chapter 20|6 pages

Glycoforms of Human Alpha1-Fetoprotein in Cancer

ByJan Brȩborowicz, Danuta Brȩborowicz, Andrzej Mackiewicz