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      Drug Toxicity and Metabolism in Pediatrics
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      Book

      Drug Toxicity and Metabolism in Pediatrics

      DOI link for Drug Toxicity and Metabolism in Pediatrics

      Drug Toxicity and Metabolism in Pediatrics book

      Drug Toxicity and Metabolism in Pediatrics

      DOI link for Drug Toxicity and Metabolism in Pediatrics

      Drug Toxicity and Metabolism in Pediatrics book

      Edited BySam Kacew
      Edition 1st Edition
      First Published 1990
      eBook Published 22 December 2017
      Pub. Location Boca Raton
      Imprint CRC Press
      DOI https://doi.org/10.1201/9781351071529
      Pages 332
      eBook ISBN 9781351071529
      Subjects Medicine, Dentistry, Nursing & Allied Health
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      Kacew, S. (Ed.). (1990). Drug Toxicity and Metabolism in Pediatrics (1st ed.). CRC Press. https://doi.org/10.1201/9781351071529

      ABSTRACT

      The aim of this text is to examine the physiological development of the fetus. It allows the reader to study the unique pharmacokinetic and metabolic features of newborns and gives specific examples of drug metabolism in the newborn. The purpose of this book is to enhance the current knowledge of pharmacology of the newborn by observing the embryo and placenta in normal and abnormal development, placental transfer of drugs, metabolic pathways, and metabolism of specific drugs such as theophylline, benzodiazepines, and antibiotics. This is a useful book for those involved in pediatric research, pharmacology, toxicology, experimental therapeutics and biology.

      TABLE OF CONTENTS

      chapter 1|14 pages

      Developmental Aspects of Pediatric Pharmacology and Toxicology

      ByS. Kacew, S. Lock

      chapter 2|20 pages

      Fetal and Neonatal Drug Biotransformation

      ByMont R. Juchau

      chapter 3|14 pages

      Effects of Cisplatin on the Chick Embryo — A Model for the Analysis of Prenatal Toxicity

      ByRoberto Narbaitz

      chapter 4|26 pages

      Pharmacology of Catecholamines

      ByArno Zaritsky

      chapter 5|42 pages

      Antidysrhythmic Drugs in Pediatrics

      ByHoward C. Mofenson, Thomas R. Caraccio, Kathleen Mimnagh, Peter Bruzzo

      chapter 6|24 pages

      Diagnosis and Management of Hypertension in Pediatrics

      ByAlbert P. Rocchini

      chapter 7|14 pages

      Pharmacology and Toxicology of Loop Diuretics in Pediatrics

      BySam Kacew

      chapter 8|18 pages

      Chloramphenicol

      BySteven R. Abel, Martin B. Kleiman

      chapter 9|12 pages

      Developmental Pharmacology of Aminoglycosides and Vancomycin

      ByGideon Koren, Julia Klein, Monica Bologa

      chapter 10|36 pages

      Toxicity of Antineoplastic Chemotherapy in Children

      ByTheodore Zwerdling, Steven K. Bergstrom, Stephen D. Smith

      chapter 11|12 pages

      Barbiturate and Nonbarbiturate Sedative Hypnotic Intoxication

      An Overview
      ByS. Bertino Joseph, Michael D. Reed

      chapter 12|8 pages

      The Role of Doxapram in Certain Pediatric Conditions

      ByS. Kacew

      chapter 13|10 pages

      Metabolism and Toxicity of Antiprostaglandin Agents

      ByCynthia R. Gelman, Barry H. Rumack

      chapter 14|14 pages

      Pharmacological and Toxicological Aspects Associated with H1 Receptor Antagonists

      ByS. Kacew

      chapter 15|30 pages

      Drugs in Gastrointestinal Disorders in Developing Infants

      BySam Kacew

      chapter 16|12 pages

      Iron Poisoning

      ByTheodore G. Tong, Banner William
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