ABSTRACT

Nutrition and Gene Expression is devoted to exploring the tissue-specific and developmental aspects of the interaction between nutrients and the genome. The book discusses chemical sensitivity in relation to the ability of cells to detect nutrients; reviews the means by which lower organisms respond to nutrients; and provides examples on how each of the classes of nutrients affects genetic transcription, mRNA translation or stability. The receptor-mediated actions of vitamin D and retinoic acid on gene expression are discussed, including the case of bone formation and dissolution. Other important topics covered in the volume include newly discovered effects of fatty acids on regulating gene expression, the effects of diet on mRNA editing, the interplay between dietary carbohydrates and proteins in regulating metabolism of liver cells, the effects of metal ions on protein synthesis, and much more.
Nutrition and Gene Expression is an important reference for nutritionists, physiologists, biochemists, clinical nutritionists, pharmaceutical researchers, geneticists, and food scientists.

chapter 1|22 pages

Nutrient Receptors And Gene Expression

ByJames L. Hargrove, Carolyn D. Berdanier

chapter 2|31 pages

Lactose Intolerance and Regulation of Small Intestinal Lactase Activity

ByRobert K. Montgomery, Hans A. Büller, Edmond Η. Η. Μ. Rings, Jan Dekker, Richard J. Grand

chapter 3|35 pages

Regulation of Gastrointestinal Lipase Gene Expression by Dietary Lipids

ByCatherine Wicker-Planquart, Antoine Puigserver

chapter 4|26 pages

Nutritional Control of Gastrointestinal Hormone Gene Expression

ByPauline Kay Lund

chapter 6|25 pages

Tissue-Specific Regulation of Glucokinase

ByMark A. Magnuson, Thomas L. Jetton

chapter 7|18 pages

Dietary and Hormonal Regulation of L-Type Pyruvate Kinase Gene Expression

ByTamio Noguchi, Takehiko Tanaka

chapter 8|20 pages

Glucose-6-Phosphate Dehydrogenase: Diet and Hormonal Influences on De Novo Enzyme Synthesis

ByRolf F. Kletzien, Carolyn D. Berdanier

chapter 9|20 pages

Nutritional and Hormonal Regulation of Genes Encoding Enzymes Involved In fat Synthesis

ByHei Sook Sul, Naima Moustaid, Kenji Sakamoto, Cynthia Smas, Nick Gekakis, Ann Jerkins

chapter 11|22 pages

Dietary Fat, Gene Expression, and Carcinogenesis

ByHoward P. Glauert

chapter 12|27 pages

Regulation of Acetyl CoA Carboxylase and Gene Expression

ByJohn B. Allred, Diana F. Bowers

chapter 13|21 pages

Apolipoprotein B mRNA Editing

ByNicholas O. Davidson

chapter 14|16 pages

Regulation of the 68-kDa Hepatic Carnitine Palmitoyltransferase

ByPaul S. Brady, Roderick A. Barke, Linda J. Brady

chapter 15|18 pages

Long-Term Regulation of Hepatic Glutaminase and the Urea Cycle Enzymes

ByMalcolm Watford

chapter 16|23 pages

Effects of Dietary Protein on Gene Expression

ByDavid K.-C. Chan, James L. Hargrove

chapter 17|14 pages

Vitamin D-Dependent Calcium Binding Protein, Calbindin-D: Regulation of Gene Expression

ByRajbir K. Gill, Sylvia Christakos

chapter 18|39 pages

Vitamin D Regulation of Osteoblast Growth and Differentiation

ByJane B. Lian, Gary S. Stein

chapter 19|24 pages

Retinoic Acid Regulation of Gene Expression in Adipocytes

ByDonald B. Jump, Gerald J. Lepar, Ormond A. MacDougald

chapter 20|27 pages

The Role of Vitamin K in Clotting Factor Biosynthesis

ByJ. W. Suttie

chapter 21|24 pages

Role of Ascorbate in Regulating the Collagen Pathway

ByRichard I. Schwarz

chapter 22|17 pages

Dietary Regulation of Metallothionein Expression

ByNeil F. Shay, Robert J. Cousins

chapter 23|21 pages

Iron-Dependent Regulation of Ferritin Synthesis

ByΗ. Ν. Munro, Ζ. Kikinis, R. S. Eisenstein

chapter 24|21 pages

Vitamin B6 Modulation of Steroid-Induced Gene Expression

ByDouglas Β. Tully, Victoria E. Allgood, John A. Cidlowski