ABSTRACT

The ability of molecular and cellular imaging to track the survival, migration, and differentiation of cells in vivo as well as monitor particular gene expression in living subjects is rapidly moving from the research laboratory into daily clinical settings. The interdisciplinary nature of the field mandates a constant dialogue among molecular and

chapter 1|9 pages

What Is Molecular and Cellular Imaging?

ByMichel M.J. Modo, Jeff W.M. Bulte

part Part I|128 pages

Contrast Agents for Molecular and Cellular Imaging

chapter 2|24 pages

Physicochemical Principles of MR Contrast Agents

ByPeter Caravan

chapter 3|22 pages

Paramagnetic Contrast Agents

BySilvio Aime, Zsolt Baranyai, Eliana Gianolio, Terreno Enzo

chapter 4|25 pages

Superparamagnetic Contrast Agents

ByClaire Corot, Marc Port, Irène Guilbert, Philippe Robert, Jean-Sebastien Raynaud, Caroline Robic, Jean-Sebastien Raynaud, Philippe Prigent, Anne Dencausse, Idée Jean-Marc

chapter 5|16 pages

Physical Mechanism and Applications of CEST Contrast Agents

ByMichael T. McMahon, Jinyuan Zhou, Assaf A. Gilad, Jeff W.M. Bulte, Peter C.M. van Zijl

chapter 6|22 pages

PARACEST Contrast Agents

ByA. Dean Sherry, Mark Woods

chapter 7|15 pages

Genetic Approaches for Modulating MRI Contrast

ByEric T. Ahrens, William F. Goins, Clinton S. Robison

part Part II|1 pages

Molecular MR Imaging

chapter 8|20 pages

Molecular and Functional MR Imaging of Cancer

ByMichael A. Jacobs, Kristine Glunde, Barjor Gimi, Arvind P. Pathak, Ellen Ackerstaff, Dmitri Artemov, Zaver M. Bhujwalla

chapter 9|21 pages

Molecular Imaging of Atherosclerosis with Magnetic Resonance

ByKaren C. Briley-Saebo, Willem J. Mulder, Fabien Hyafil, Venkatesh Mani, Vardan Amirbekian, Juan Gilberto S. Aguinaldo, James F. Rudd, Silvia H. Aguiar, Zahi A. Fayad

chapter 10|16 pages

Molecular Imaging of Apoptosis

ByMikko I. Kettunen, Kevin M. Brindle

chapter 11|19 pages

Molecular Imaging of Reporter Genes

ByKeren Ziv, Dorit Granot, Vicki Plaks, Batya Cohen, Michal Neeman

chapter 12|25 pages

Pharmacological MRI as a Molecular Imaging Technique

ByY. Iris Chen, Bruce G. Jenkins

part Part III|148 pages

Cellular MR Imaging

chapter 13|11 pages

Cellular MR Imaging of the Liver Using Contrast Agents

ByN. Cem Balci, Sukru Mehmet Erturk

chapter 14|14 pages

Cellular Imaging of Macrophage Activity in Infection and Inflammation

ByMartin Rausch, Markus Rudin, Peter R. Allegrini, Nicolau Beckmann

chapter 15|10 pages

Cellular Imaging of Macrophage Activity in Stroke

ByRalph Weber, Mathias Hoehn

chapter 16|12 pages

Magnetic Resonance Imaging in Developmental Biology

ByCyrus Papan, J. Michael Tyszka, Russell E. Jacobs

chapter 17|22 pages

Methods for Labeling Nonphagocytic Cells with MR Contrast Agents

ByJoseph A. Frank, Stasia A. Anderson, Ali S. Arbab

chapter 18|13 pages

Cellular Imaging of Cell Transplants

ByMichel M.J. Modo, Jeff W.M. Bulte

chapter 19|21 pages

Cellular and Molecular Imaging of the Diabetic Pancreas

ByZdravka Medarova, Anna Moore

chapter 20|24 pages

Functional Cellular Imaging with Manganese

ByVincent Van Meir, Annemie Van der Linden

part Part IV|17 pages

Cellular MR Imaging

chapter 21|9 pages

Translating Promising Experimental Approaches to Clinical Trials

ByAdrian D. Nunn

chapter 22|5 pages

An Outlook on Molecular and Cellular MR Imaging

ByMichel M.J. Modo, Jeff W.M. Bulte

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