ABSTRACT

The drug discovery and development process is getting longer, more expensive, and no better. The industry suffers from the same clinical attrition and safety-related market withdrawal rates today as it did 20 years ago. Industrialization of Drug Discovery: From Target Selection Through Lead Optimization scrutinizes these problems in detail, contras

chapter 2|18 pages

The Regulatory Age

BySandy Weinberg

chapter 3|26 pages

Industrialization, Not Automation

ByTim Peakman

chapter 4|46 pages

Compound Management

ByEric D. Perakslis, Terry V. Iorns

chapter 5|34 pages

High-Throughput Screening

ByMark Beggs, Victoria Emerick, Richard Archer

chapter 6|28 pages

Parallel Lead Optimization

BySteven L. Gallion, Alan Beresford, Philippe Bey

chapter 7|26 pages

Knowledge Management

ByBeverly Buckta

chapter 8|28 pages

Understanding the Value of Research

ByPaul Bussey, Jo Pisani, Yann Bonduelle

chapter 9|26 pages

Collaboration in a Virtual and Global Environment

ByJohn Barrett

chapter 10|46 pages

From Genome to Drug: Ethical Issues

ByPatricia Deverka, David Magnus