The Antibodies presents models, theories, and techniques of molecular biology for understanding the mechanisms of antibody action, including the genetics, and receptor and channel action. This book includes applications of engineered antibodies in diagnosis, immunotherapy, and protein purification. It provides new insights into the structural basis

chapter 1|24 pages

Regulation and Expression of Immunoglobulin Heavy Chains

ByCarol F. Webb, Kent Buchanan, Shenshen Dou, Elizabeth Smith, Yoshio Yamashita

chapter 2|26 pages

Antibody-Based Mechanisms of Tumor Immunity

ByAllison M. Watts, Ronald C. Kennedy, Robert K. Bright

chapter 3|14 pages

The Human Antibody Repertoire: Old Notions, Current Realities, and VH Gene-Dependent Biases

ByAnnuska M. Glas, Erwin H. N. van Montfort, Eric C. B. Milner

chapter 4|21 pages

Understanding Human Immunoglobulin Repertoires in vivo and Evolving Specificities in vitro

ByM. Ohlin, P. Jirholt, H. B. Thosteinsdottir, C. A. K. Borrebaeck

chapter 7|42 pages

Regulation of B-Cell Activation by the Co-Receptors: The CD19 Connection

BySidne A. Omori, Dennis C. Otero, Robert C. Rickert