Examines Critical Decisions for Transitioning Lab Science to a Clinical SettingThe development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing. As a result, translational medicine (TM) is becoming increasingly important in

chapter 1|8 pages

Translational Medicine: Strategies and Statistical Methods

ByDennis Cosmatos, Shein-Chung Chow

chapter 2|24 pages

Strategic Concepts in Translational Medicine

ByDennis Cosmatos, Giora Feuerstein, Shein-Chung Chow

chapter 3|42 pages

Design and Analysis Approaches for Discovery Translational Medicine

ByDennis Cosmatos and Shein-Chung Chow (Eds.) and Stephen B. Forlow, Jennifer A. Isler, Zhaosheng Lin, and Michael E. Burczynski, with Statistical Appendix by Jessie Q. Xia and S. Stanley Young

chapter 4|18 pages

Biomarker Development

ByMark Chang

chapter 5|26 pages

Targeted Clinical Trials

ByJen-pei Liu

chapter 6|28 pages

Statistical Methods in Translational Medicine

ByShein-Chung Chow, Siu-Keung Tse, Dennis Cosmatos

chapter 7|22 pages

Nonparametric Methods in Translational Research

ByKongming Wang, Shein-Chung Chow

chapter 8|22 pages

Model Selection/Validation*

ByJen-pei Liu

chapter 9|14 pages

Translation in Clinical Information between Populations—Bridging Studies

ByChin-Fu Hsiao, Mey Wang, Herng-Der Chern, and Jen-pei Liu

chapter 10|14 pages

Translation in Clinical Technology—Traditional Chinese Medicine

ByChin-Fu Hsiao, Hsiao-Hui Tsou, Shein-Chung Chow