Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to the clinic of targeted imaging agents. The many case studies t

part |2 pages

Part I: In Vitro Studies

chapter 1|14 pages

In Vitro Approaches to Site-Specic Imaging Agents

ByRaymond E. Gibson

part |2 pages

Part II: Small Animal Studies

chapter 2|18 pages

Small Animal Tumor Models for Use in Imaging

ByCheryl L. Marks

chapter 3|34 pages

Animal Models in Cardiology

ByWengen Chen, Henry Gewirtz, Mark Smith, Vasken Dilsizian

chapter 4|18 pages

Imaging Diabetes in Small Animals: Models, Methods, and Targets

ByKooresh I. Shoghi

part |2 pages

Part III: Radiopharmacology and Radiopharmacy

part |2 pages

Part IV: Case Studies on Developing Targeted Nonnuclear Probes

part |2 pages

Part V: Case Studies on Developing Targeted Radiotracers

chapter 10|26 pages

Imaging Infection Based on Expression of Thymidine Kinase

ByChetan Bettegowda, Youngjoo Byun, Catherine A. Foss, George Sgouros, Richard F. Ambinder, and Martin G. Pomper

chapter 12|14 pages

Radioligands for the Vesicular Monoamine Transporter Type 2

ByMichael R. Kilbourn

chapter 13|22 pages

Radiopharmaceuticals for Imaging Proliferation

ByKenneth A. Krohn, John R. Grierson, Mark Muzi, Jeffrey L. Schwartz

chapter 14|10 pages

[99mTc]TRODAT: Dopamine Transporter Imaging Agent for SPECT

ByHank F. Kung, Karl Ploessl

chapter 16|26 pages

Steroid Hormone Ligands for the Estrogen Receptor

ByDavid A. Mankoff, Jeanne M. Link, Hannah M. Linden