ABSTRACT
Addressing the many challenges that have arisen since the publication of its predecessor, this third edition covers the newest developments involved in the design and analysis of cancer clinical trials. Accessible to statisticians in clinical trials as well as oncologists interested in clinical trial methodology, the book presents up-to-date statistical approaches to the design and analysis of oncology clinical trials. New topics in this edition include trial designs for targeted agents, Bayesian trial design, and the inclusion of high-dimensional data and imaging techniques. This edition also contains numerous figures and examples to better explain concepts.
TABLE OF CONTENTS
part Part I|106 pages
Phase I Trials
part Part II|76 pages
Phase II Trials
chapter 11|12 pages
Phase II with Multiple Subgroups
part Part III|230 pages
Phase III Trials
part Part IV|205 pages
Exploratory and High-Dimensional Data Analyses