Modern brachytherapy is one of the most important oncological treatment modalities requiring an integrated approach that utilizes new technologies, advanced clinical imaging facilities, and a thorough understanding of the radiobiological effects on different tissues, the principles of physics, dosimetry techniques and protocols, and clinical expertise. A complete overview of the field, Comprehensive Brachytherapy: Physical and Clinical Aspects is a landmark publication, presenting a detailed account of the underlying physics, design, and implementation of the techniques, along with practical guidance for practitioners.

Bridging the gap between research and application, this single source brings together the technological basis, radiation dosimetry, quality assurance, and fundamentals of brachytherapy. In addition, it presents discussion of the most recent clinical practice in brachytherapy including prostate, gynecology, breast, and other clinical treatment sites. Along with exploring new clinical protocols, it discusses major advances in imaging, robotics, dosimetry, Monte Carlo-based dose calculation, and optimization.

chapter 1|6 pages

- Introduction and Innovations in Brachytherapy

ByJack L. M. Venselaar, Dimos Baltas, Peter Hoskin, Ali S. Meigooni

chapter 2|20 pages

- Standard Technology in Brachytherapy

ByRupak K. Das, Jack L. M. Venselaar

chapter 3|14 pages

- Radionuclides in Brachytherapy: Current and Potential New Sources

ByFacundo Ballester, Ravinder Nath, Dimos Baltas

chapter 4|18 pages

- Quality Assurance of Equipment

ByJack L. M. Venselaar, Firas Mourtada

chapter 5|14 pages

- Source Calibration

ByHans Bjerke, Larry A. DeWerd, Jan P. Seuntjens, and Margaret Bidmead

chapter 6|10 pages

- Experimental Dosimetry Methods

ByDimos Baltas, Brigitte Reniers, Ali S. Meigooni

chapter 7|22 pages

- Computational Methods for Dosimetric Characterization of Brachytherapy Sources

ByPanagiotis Papagiannis, Luc Beaulieu, Firas Mourtada

chapter 8|10 pages

- Historical Development of Predictive Dosimetry “Systems”

ByAli S. Meigooni, Margaret Bidmead, Jack L. M. Venselaar

chapter 9|20 pages

- Two-, Three-, and Four-Dimensional Brachytherapy

ByJean Pouliot, Ron Sloboda, Brigitte Reniers

chapter 10|8 pages

- TG-43 Dose Calculation Formalism: Development, Insights, and Modernization

ByMark J. Rivard, Ali S. Meigooni, Ravinder Nath

chapter 12|16 pages

- Optimization and Evaluation

ByDimos Baltas and Inger-Karine K. Kolkman-Deurloo

chapter 13|14 pages

- Quality Management of Treatment Planning

ByAli S. Meigooni, Jack L. M. Venselaar

chapter 14|22 pages

- Practical Use, Limitations, and Quality Control of Imaging in Brachytherapy

ByFrank-André Siebert, Taran Paulsen Hellebust

chapter 15|12 pages

- Uncertainties Associated with Brachytherapy Source Calibrations and Dose Calculations

ByLarry A. DeWerd, Mark J. Rivard, and Hans-Joachim Selbach

chapter 16|10 pages

- Uncertainties Associated with Clinical Aspects of Brachytherapy

ByPeter Hoskin, Alfredo Polo, Jack L. M. Venselaar

chapter 17|12 pages

Margin Concepts in Image- Guided Brachytherapy

ByKari Tanderup, Christian Kirisits, Jacob C. Lindegaard, Erik Van Limbergen, André Wambersie, Richard Pötter

chapter 18|6 pages

- Clinical Use of Brachytherapy

ByPeter Hoskin

chapter 19|18 pages

- Radiobiology for Brachytherapy

ByDavid J. Carlson, Zhe J. Chen, Peter Hoskin, Zoubir Ouhib, Marco Zaider

chapter 20|24 pages

- Brachytherapy for Prostate Cancer

ByAlfredo Polo, Michel Ghilezan

chapter 21|24 pages

- Brachytherapy for Gynecologic Cancers

ByBeth Erickson, Mahesh Kudrimoti, Christine Haie-Meder

chapter 22|18 pages

- Brachytherapy for Breast Cancer

ByKara Lynne Leonard, Erik Van Limbergen

chapter 23|32 pages

- Brachytherapy for Other Treatment Sites

ByVratislav Strnad, Beth Erickson, Mahesh Kudrimoti

chapter 25|18 pages

- In Vivo Dosimetry in Brachytherapy

ByJoanna E. Cygler, Kari Tanderup, Sam Beddar, José Pérez-Calatayud

chapter 26|12 pages

- Special Brachytherapy Modalities

ByChristopher S. Melhus, Mark J. Rivard, Ravinder Nath

chapter 27|18 pages

- Advanced Brachytherapy Technologies: Encapsulation, Ultrasound, and Robotics

ByMark J. Rivard, Luc Beaulieu, Marinus A. Moerland

chapter 28|8 pages

- Intraoperative Brachytherapy

ByJoost Jan Nuyttens, Subir Nag

chapter 29|12 pages

- Radiation Protection in Brachytherapy

ByPanagiotis Papagiannis, Ning J. Yue

chapter 30|14 pages

- New Paradigm for Quality Management in Brachytherapy

BySusan Richardson, Geethpriya Palaniswaamy, Sasa Mutic, Eric Klein

chapter 31|14 pages

- Quality Audits in Brachytherapy

ByCarlos de Almeida, David Followill, and Claudio Sibata

chapter 32|18 pages

- Expert Training in Brachytherapy

ByAlex Rijnders, Zoubir Ouhib, György Kovács, Peter Grimm