Highlighting the latest advances in molecular biology, mathematical modeling, quantitative risk assessment, and biopharmaceutical development, this reference presents how current scientific applications and methods impact and revolutionize mainstream toxicological research. Presenting findings from disciplines that will impact the future of toxicol

chapter 1|4 pages

Introduction and Overview

ByJim E. Riviere

chapter 2|20 pages

Toxicogenomics: Gene Expression Analysis and Computational Tools

ByRupesh P. Amin, Hisham K. Hamadeh, J. Todd Auman, Lee Bennett, Cynthia A. Afshari, Pierre R. Bushel, Richard S. Paules, J. Christopher Corton

chapter 3|22 pages


ByFrank A. Witzmann

chapter 4|14 pages

The Potential of Metabonomics in Toxicology

ByJulian L. Griffin

chapter 5|22 pages

Quantitative Structure–Toxicity Relationships Using Chemodescriptors and Biodescriptors

BySubhash C. Basak, Denise Mills, Brian D. Gute

chapter 6|10 pages

Hormesis: A Key Concept in Toxicology

ByEdward J. Calabrese

chapter 7|24 pages

Chemical Risk Assessment

ByRonald E. Baynes, Jennifer L. Buur

chapter 9|16 pages

Validation of In Vitro Methods for Toxicology Studies

ByWilliam S. Stokes

chapter 10|28 pages

Chemical Mixtures Risk Assessment and Technological Advances

ByM. M. Mumtaz, B. A. Fowler, C. T. De Rosa, P. Ruiz, M. Whittaker, J. Dennison

chapter 11|12 pages

Risk-Based Approach to Foods Derived from Genetically Engineered Animals

ByLarisa Rudenko, Kevin J. Greenlees, and John C. Matheson III

chapter 12|18 pages

Toxicology of Nanomaterials

ByNancy A. Monteiro-Riviere, Jessica P. Ryman-Rasmussen

chapter 13|14 pages

The Biological Basis of Experimental Toxicity of Jet Propulsion Fuel–8

BySimon S. Wong, Mark L. Witten

chapter 14|24 pages

Drug Safety Toxicology

ByJoseph P. Hanig, Robert E. Osterberg

chapter 15|24 pages

Statins and Toxicity

ByJohn Farmer

chapter 16|68 pages

Inhalation Toxicology

ByRoger O. McClellan, Michele A. Medinsky, M. Burton Snipes

chapter 17|22 pages

Modern Gas Chromatography–Mass Spectrometry in Human Forensic Toxicology

ByBeat Aebi, Werner Bernhard