ABSTRACT

Bridging the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments, this book describes major areas of progress in the laboratory and clinic. In the first section, aspects of cellular organelles are discussed. The second section covers the basic principles and applications of modern

part |2 pages

Section I

chapter 1|16 pages

Cellular Organelle-based Renal Toxicity

ByYoung-Jin Chun

part |2 pages

Section II

chapter 2|21 pages

Transcriptomic Approaches to Toxicity Assessment#

ByDal Woong Choi, Woonun Jung, Il Je Cho, Min Sung Joo, Chan Gyu Lee, Sang Woo Lim, Sang Geon Kim

chapter 3|35 pages

Proteomic Approaches to Toxicity Assessment

BySun Young Kim, So Jung Son, Aree Moon

part |2 pages

Section III

chapter 5|18 pages

In Silico Approaches to Study Drug-induced Renal Toxicity

ByRajiv Gandhi Govindaraj, Prasannavenkatesh Durai, Sangdun Choi

chapter 6|19 pages

Systems Toxicology Approaches

ByHyobin Jeong, Sang Chul Rho, Daehee Hwang

chapter 7|17 pages

Introduction to Virtual Cell and its Possible Application to Toxicity

ByJi-Young Hong, Eun Bo Shim, Kwang Hyun Cho

part |2 pages

Section IV

chapter 8|16 pages

Molecular Pathology of Renal Fibrosis

ByInah Hwang, Joo young Huh and Hunjoo Ha

chapter 9|14 pages

Clinical Implications of Renal Toxicity

ByDuk-Hee Kang

part |2 pages

Section V

chapter 10|14 pages

Classifi cation of Nephrotoxicants

ByHang-Sik Roh, Jong-Kwon Lee, Tae-Sung Kim, Ji-Hyeon Seok, Ji-Hyun Yun, Ji-Young Yun, Saet-Byul Oh, Soon-Young Han, Jayoung Jeong