ABSTRACT

Edited by renowned protein scientist and bestselling author Roger L. Lundblad, with the assistance of Fiona M. Macdonald of CRC Press, this fifth edition of the Handbook of Biochemistry and Molecular Biology gathers a wealth of information not easily obtained, including information not found on the web.

Presented in an organized, concise, and simple-to-use format, this popular reference allows quick access to the most frequently used data. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents. An entirely new section on Chemical Biology and Drug Design gathers data on amino acid antagonists, click chemistry, plus glossaries for computational drug design and medicinal chemistry. Each table is exhaustively referenced, giving the user a quick entry point into the primary literature.

New tables for this edition:

  • Chromatographic methods and solvents
  • Protein spectroscopy
  • Partial volumes of amino acids
  • Matrix Metalloproteinases
  • Gene Editing
  • Click Chemistry

section I|239 pages

Amino Acids, Peptides, and Proteins

chapter |4 pages

Properties of Amino Acids

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |25 pages

Data on the Naturally Occurring Amino Acids

ByElizabeth Dodd Mooz

chapter |1 pages

Coefficients Of Solubility Equations Of Certain Amino Acids In Watera

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Solubilities of Amino Acids in Water at Various Temperatures

ByJohn O. Hutchens

chapter |2 pages

Heats of Solution of Amino Acids in Aqueous Solution at 25° C

ByJohn O. Hutchens

chapter |1 pages

Free Energies of Solution and Standard Free Energy of Formation of Amino Acids in Aqueous Solution at 25° C

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |2 pages

Far Ultraviolet Absorption Spectra of Amino Acids

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |5 pages

Numerical Values of the Absorbances of the Aromatic Amino Acids in Acid, Neutral, and Alkaline Solutions

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |15 pages

Hydrophobicities of Amino Acids and Proteins

ByC. C. Bigelow, M. Channon

chapter |3 pages

Partial Volumes of Amino Acidsa

ByRoger L. Lundblad

chapter |2 pages

Deamidation of Asparagine

ByRoger L. Lundblad

chapter |4 pages

Michael Reactions of Proteins

ByRoger L. Lundblad

chapter |1 pages

Temperature Coefficients of Apparent Partial Specific Volumes of Proteins Expressed in ml/g/deg (dV/dT)

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |4 pages

Protein pK Values

ByLynne H. Botelho, Frank R. N. Gurd

chapter |2 pages

Intrinsic Viscosity of Proteins

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Infrared Spectra of Proteins

ByH. Susi

chapter |1 pages

Volume Changes for Some Macromolecule Association Reactions

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |5 pages

Assay of Solution Protein Concentration

ByRoger L. Lundblad

section II|54 pages

Enzymes

chapter |4 pages

Turnover of Enzymes in Tissues

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Molecular Turnover of Cytochromes in Animals

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |12 pages

Matrix Metalloproteinases

ByRoger L. Lundblad

chapter |8 pages

Proteases in the Interstitial Space

ByRoger L. Lundblad

chapter |11 pages

Enzymes in Synthetic Organic Chemistrya,b

ByRoger L. Lundblad

chapter |4 pages

Therapeutic Enzymesa

ByRoger L. Lundblad

chapter |13 pages

Protease Inhibitors and Protease Inhibitor Cocktails

ByRoger L. Lundblad

section III|56 pages

Lipidomics and Lipidomes

chapter |1 pages

Evolution of the Classification and Nomenclature of Lipids

ByRoger L. Lundblad

chapter |1 pages

A Brief Glossary for Lipidomics

ByRoger L. Lundblad

chapter |24 pages

A Comprehensive Classification System for Lipids 1

ByEoin Fahy, Shankar Subramaniam, H. Alex Brown, Christopher K. Glass, Alfred H. Merrill, Robert C. Murphy, Christian R. H. Raetz, David W. Russell, Yousuke Seyama, Walter Shaw, Takao Shimizu, Friedrich Spener, Gerrit van Meer, Michael S. Van Nieuwenhze, Stephen H. White, Joseph L. Witztum, Edward A. Dennis

chapter |2 pages

Properties of Fatty Acids and Their Methyl Esters

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Densities, Specific Volumes, and Temperature Coefficients of Fatty Acids From C8 to C12

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |4 pages

Composition and Properties of Common Oils and Fats

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |6 pages

Spectral Properties of Fatty Acids

ByRoger L. Lundblad

chapter |4 pages

IR Active Bands of Phosphatidylethanolamines (PE)

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |5 pages

Some Unusual Fatty Acid Structures

ByRoger L. Lundblad

section IV|23 pages

Vitamins and Coenzymes

chapter |10 pages

Properties of Vitamins

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |3 pages

Biological Characteristics of Vitamins

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |8 pages

Vitamers

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Vitamin Names Discarded

Edited ByRoger L. Lundblad, Fiona M. Macdonald

section V|124 pages

Nucleic Acids

chapter |4 pages

Some Definitions For Nucleic Acids

ByRoger L. Lundblad

chapter |1 pages

Ultraviolet Absorbance of Oligonucleotides Containing 2′-O-Methylpentosea Residues

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |3 pages

Spectrophotometric Constants of Ribonucleotides

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |13 pages

Chemical Modification of Nucleic Acids

ByRoger L. Lundblad

chapter |3 pages

Polymerase Chain Reaction

ByRoger L. Lundblad

chapter |4 pages

Gene Editing

ByRoger L. Lundblad

section VI|30 pages

Glycoscience

chapter |7 pages

Nomenclature of Carbohydrates

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |9 pages

Chemical Modification of Carbohydrates

ByRoger L. Lundblad

chapter |6 pages

Some Properties of Glycosaminoglycans

ByRoger L. Lundblad

chapter |3 pages

Sugar Mimetics

ByRoger L. Lundblad

chapter |4 pages

Intrinsic Viscosity of Polysaccharides

ByRoger L. Lundblad

section VII|30 pages

Chemical Biology and Drug Design

chapter |2 pages

Unnatural Amino Acids for Incorporation into Proteins

ByRoger L. Lundblad

chapter |2 pages

Properties of the α-Keto Acid Analogs of Amino Acids

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

α,β-Unsaturated Amino Acids

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |6 pages

Amino Acid Antagonists

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Particle Diameter

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Weights of Cells and Cell Constituents

ByNorman G. Anderson

chapter |4 pages

Click Chemistry

ByRoger L. Lundblad

section VIII|419 pages

Physical and Chemical Data

chapter |3 pages

Standard Transformed Gibbs Energies of Formation for Biochemical Reactants

ByRobert N. Goldberg, Robert A. Alberty

chapter |1 pages

Enthalpy, Entropy, and Free Energy Values for Biochemical Redox Reactions

(Data are reported for pH 7.0 and 298 K)
Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |11 pages

Calorimetric ΔH Values Accompanying Conformational Changes of Macromolecules in Solution

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |4 pages

Free Energies of Hydrolysis and Decarboxylation

ByWilliam P. Jencks

chapter |1 pages

Deci-Normal Solutions of Oxidation and Reduction Reagents

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |7 pages

Guidelines for Potentiometric Measurements in Suspensions Part A — The Suspension Effect 1

(IUPAC Technical Report)
BySrecko F. Oman, M. Filomena Camões, Kipton J. Powell, Raj Rajagopalan, and Petra Spitzer

chapter |41 pages

Ionization Constants of Acids and Bases

ByW. P. Jencks, J. Regenstein

chapter |7 pages

Guidelines for NMR Measurements for Determination of High and Low pK a Values1

(IUPAC Technical Report)
ByKonstantin Popov, Hannu Rönkkömäki, Lauri H. J. Lajunen

chapter |28 pages

Measurement and Interpretation of Electrokinetic Phenomena

(IUPAC Technical Report)
ByA. V. Delgado, F. González-Caballero, R. J. Hunter, L. K. Koopal, J. Lyklema

chapter |17 pages

Measurement of pH Definition, Standards, and Procedures

(IUPAC Recommendations 2002)
ByR. P. Buck, S. Rondinini, A. K. Covington, F. G. K. Baucke, C. M. A. Brett, M. F. Camões, M. J. T. Milton, T. Mussini, R. Naumann, K. W. Pratt, P. Spitzer, and G. S. Wilson

chapter |2 pages

General Comments on Buffers

ByRoger L. Lundblad

chapter |12 pages

List of Buffers

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Brønsted Acidities

ByRoger L. Lundblad

chapter |4 pages

Buffer Solutions

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Amine Buffers Useful for Biological Research

ByNorman Good

chapter |4 pages

Preparation of Buffers for Use in Enzyme Studies*

ByG. Gomori

chapter |2 pages

Indicators for Volumetric Work and pH Determinations

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |4 pages

Acid and Base Indicators

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |4 pages

Specific Gravity of Liquids

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |4 pages

Properties of Some Solvents

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |2 pages

Common Detergents Used in Biochemical Research

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |3 pages

Some Properties of Detergents and Surfactants Used in Biochemistry and Molecular Biology

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |23 pages

Some Biological Stains and Dyes

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |3 pages

Mordant Dyes

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |8 pages

Metal Chelating Agentsa

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |7 pages

Metallomics: Guidelines for Terminology and Critical Evaluation of Analytical Chemistry Approaches (IUPAC Technical Report)*

ByRyszard Lobinski, J. Sabine Becker, Hiroki Haraguchi, Bibundhendra Sarkar

chapter |2 pages

Water

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |2 pages

General Information on Spectroscopy

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |6 pages

Plastics

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |1 pages

Chemical and Physical Properties of Various Commercial Plastics

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |2 pages

Chemical Resistance of Plastics

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |6 pages

Generic Source-Based Nomenclature for Polymers

(IUPAC Recommendations 2001): Prepared by a Working Group consisting of
ByR. E. Bareiss, R. B. Fox, K. Hatada, K. Horie, A. D. Jenkins, J. Kahovec, R Kubisa, E. Maréchal, I. Meisel, W. V. Metanomski, I. Mita, R. F. T. Stepto, E. S. Wilks, E. Maréchal, E. S. Wilks

chapter |8 pages

Definitions of Terms Relating to Reactions of Polymers and to Functional Polymeric Materials

(IUPAC Recommendations 2003): Prepared by a Working Group consisting of
ByK. Horie, M. Barón, R. B. Fox, J. He, M. Hess, J. Kahovec, T. Kitayama, P. Kubisa, E. Maréchal, W. Mormann, R. F. T. Stepto, D. Tabak, J. Vohlídal, E. S. Wilks, W. J. Work

chapter |11 pages

Definitions of Terms Related to Polymer Blends, Composites, and Multiphase Polymeric Materials

(IUPAC Recommendations 2004): Prepared by a Working Group consisting of
ByW. J. Work, K. Horie, M. Hess, R. F. T. Stepto, W. J. Work

chapter |16 pages

Terminology For Biorelated Polymers And Applications (Iupac Recommendations 2012)*

ByMichel Vert, Yoshiharu Doi, Karl-Heinz Hellwich, Michael Hess, Philip Hodge, Przemyslaw Kubisa, Marguerite Rinaudo, François Schué

chapter |2 pages

Intrinsic Viscosity of Poly(ethylene glycol)

ByRoger L. Lundblad

chapter |13 pages

International Union of Pure and Applied Chemistry Physical Chemistry Division Commission on Molecular Structure and Spectroscopy*

Nmr Nomenclature – Nuclear Spin Properties and Conventions For Chemical Shifts: (IUPAC Recommendations 2001): Prepared for publication by
ByRobin K. Harris, Edwin D. Becker, Sonia M. Cabral De Menezes, Robin Goodfellow, Pierre Granger

chapter |7 pages

Brief guide to the nomenclature of inorganic chemistry

IUPAC Technical Report
ByRichard M. Hartshorn, Karl-Heinz Hellwich, Andrey Yerin, Ture Damhus, Alan T. Hutton

chapter |2 pages

Properties of Fluorescent Probes Commonly Used for Membrane Studies

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |16 pages

Chromatography

ByRoger L. Lundblad

chapter |2 pages

Blotting Technologies

Edited ByRoger L. Lundblad, Fiona M. Macdonald

chapter |3 pages

Oxidation of Thiols

ByRoger L. Lundblad

chapter |2 pages

Partial Volumes for Some Selected Compounds

Edited ByRoger L. Lundblad, Fiona M. Macdonald