Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures.

Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text:

  • Presents the principles and applications of bioprinting
  • Discusses bioinks for 3D printing
  • Explores applications of extrusion bioprinting, including past, present, and future challenges
  • Includes discussion on 4D Bioprinting in terms of mechanisms and applications

chapter 1|24 pages

Principles and applications of bioprinting

ByA. Skardal

chapter 2|26 pages

Bioinks for 3D printing

ByE. Gargus, P. Lewis, R. Shah

chapter 3|25 pages

Applications of extrusion bioprinting

Past, present, future
ByG. Forgacs, F. Marga, K. Jakab

chapter 4|22 pages

Laser-based 3D bioprinting

ByBenjamin T. Vinson, S.C. Sklare, Yong Huang, Douglas B. Chrisey

chapter 5|20 pages

Inkjet-based 3D bioprinting

ByShibu Chameettachal, Falguni Pati

chapter 6|26 pages

Rapid prototyping of soft bioactuators

ByCaroline Cvetkovic, Eunkyung Ko, Collin Kaufman, Lauren Grant, Martha Gillette, Hyunjoon Kong, Rashid Bashir

chapter 7|13 pages

Bioprinting in otolaryngology and airway reconstruction

ByDavid A. Zopf, Glenn E. Green

chapter 8|22 pages

Bioprinting of human skin

Gaps, opportunities, and future directions
ByTania Baltazar, Carolina Catarino, Pankaj Karande

chapter 9|19 pages

Bioprinting vascular networks

ByVivian K. Lee, Guohao Dai

chapter 10|45 pages

Bioprinting of living aortic valve

ByD.Y. Cheung, S. Wu, B. Duan, J.T. Butcher

chapter 11|22 pages

3D bioprinting of cardiac muscle tissue

ByAndrew Lee, Adam W. Feinberg

chapter 12|23 pages

Additive manufacturing in the craniofacial area

Applications in vertical alveolar bone augmentation
ByCedryck Vaquette, Kelly McGowan, Saso Ivanovski

chapter 13|19 pages

Bioprinting of liver

ByDong-Woo Cho, Hyungseok Lee, Wonil Han, Yeong-Jin Choi

chapter 14|23 pages

Bioprinting-enabled technologies for cryopreservation

ByFariba Ghaderinezhad, Reza Amin, Savas Tasoglu

chapter 15|22 pages

4D bioprinting

Mechanism and applications
ByQingzhen Yang, Yuan Ji, Feng Xu

chapter 16|15 pages

Current challenges and future perspectives of bioprinting

ByM. Varkey, A. Atala