The Ischemic Penumbra presents the current status of concepts and research on this topic and identifies the latest methods for clinicians to quickly and efficiently recognize viable cerebral tissue for enhanced stroke management. Focusing on state-of-the-science technologies and current trends, the book examines imaging strategies utilizing PET, SP

chapter 2|14 pages

The Ischemic Penumbra: Overview, Definition, and Criteria

ByGeoffrey A. Donnan, Jean-Claude Baron, Stephen M. Davis, Frank R. Sharp

chapter 3|16 pages

Perfusion Thresholds in Cerebral Ischemia

ByRamez R. Moustafa, Jean-Claude Baron

chapter 4|22 pages

Duration and Thresholds of the Ischemic Penumbra in Different Species

ByOmar Touzani, Jean-Claude Baron

chapter 5|18 pages

The Ischemic Cascade: Events Within the Penumbra

ByJuliane Klehmet, Ulrich Dirnagl, Jens Peter Dreier, Andreas Meisel

chapter 6|16 pages

Multimodal Mapping of the Ischemic Penumbra in Animal Models

ByKonstantin-A. Hossmann and Günter Mies

chapter 7|16 pages

Molecular Biology of the Penumbra

ByFrank R. Sharp, Huichun Xu, Xinshe Liu, Ruiqiong Ran

chapter 8|16 pages

Selective Neuronal Loss

ByAnthony J. Strong, Anna M. Planas

chapter 9|12 pages

Inflammation and Reperfusion Injury Within the Penumbra

ByAdrian Parry-Jones, Johann R. Selvarajah, Pippa J. Tyrrell, Nancy J. Rothwell

chapter 11|16 pages

Imaging the Penumbra: Positron Emission Tomography Fluoromisonidazole

ByNeil J. Spratt, David W. Howells, Geoffrey A. Donnan

chapter 18|12 pages

The Topography of the Ischemic Penumbra

chapter 19|18 pages

The Penumbra and Intracerebral Hemorrhage