Drug Stereochemistry: Analytical Methods and Pharmacology, Third Edition covers all aspects of chiral drugs from academic, governmental, industrial, and clinical perspectives, reflecting the many advances in techniques and methodology. Topics include:The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug disc

chapter 2|13 pages

Stereochemistry—basic terms and concepts

ByKrzysztof Jo´z´wiak

chapter 3|18 pages

Molecular basis of chiral recognition

ByKrzysztof Jo´z´wiak

chapter 8|20 pages

Enantioselective separations by electromigration techniques

ByMichał J. Markuszewski

chapter 10|11 pages

Stereoselective transport of drugs

ByPrateek Bhatia, Ruin Moaddel

chapter 11|24 pages

Enantioselective binding of drugs to plasma proteins

ByThomas H. Kim

chapter 12|34 pages

Clinical pharmacokinetics and pharmacodynamics of stereoisomeric drugs

ByScott A. Van Wart, Donald E. Mager

chapter 13|34 pages

Regulatory perspective on the development of new stereoisomeric drugs

BySarah K. Branch, Andrew J. Hutt

chapter 14|20 pages

Molecular analysis of agonist stereoisomers at b2-adrenoceptors

ByRoland Seifert, Stefan Dove

chapter 16|9 pages

The importance of chiral separations in single enantiomer patent cases

ByCharlotte Weekes