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      Book

      Philosophy of Molecular Medicine
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      Book

      Philosophy of Molecular Medicine

      DOI link for Philosophy of Molecular Medicine

      Philosophy of Molecular Medicine book

      Foundational Issues in Research and Practice

      Philosophy of Molecular Medicine

      DOI link for Philosophy of Molecular Medicine

      Philosophy of Molecular Medicine book

      Foundational Issues in Research and Practice
      Edited ByGiovanni Boniolo, Marco J. Nathan
      Edition 1st Edition
      First Published 2016
      eBook Published 9 November 2016
      Pub. Location New York
      Imprint Routledge
      DOI https://doi.org/10.4324/9781315674162
      Pages 296
      eBook ISBN 9781315674162
      Subjects Bioscience, Humanities, Medicine, Dentistry, Nursing & Allied Health
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      Boniolo, G., & Nathan, M.J. (Eds.). (2016). Philosophy of Molecular Medicine: Foundational Issues in Research and Practice (1st ed.). Routledge. https://doi.org/10.4324/9781315674162

      ABSTRACT

      Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.

      TABLE OF CONTENTS

      chapter |12 pages

      Introduction

      ByGIOVANNI BONIOLO, MARCO J. NATHAN

      part |2 pages

      Part I Nature, Origins, and Scope

      chapter 1|20 pages

      Molecular Medicine: The Clinical Method Enters the Lab

      ByGIOVANNI BONIOLO

      chapter 2|22 pages

      Personalized Medicine: Historical Roots of a Medical Model

      ByMARIACARLA GADEBUSCH BONDIO AND FRANCESCO SPÖRING

      chapter 3|22 pages

      From the Concept of Genetic Disease to the Geneticization of Diseases: Analyzing and Solving the Paradox of MARIE DARRASON

      ByContemporary Medical Genetics

      part |2 pages

      Part II Explanation

      chapter 4|19 pages

      Molecular Complexity: Why Has Psychiatry Not Been Revolutionized by Genomics (Yet)?

      ByMAËL LEMOINE

      chapter 5|22 pages

      How Cancer Spreads: Reconceptualizing a Disease

      ByKATHERINE E. LIU, ALAN C. LOVE, MICHAEL TRAVISANO

      chapter 6|23 pages

      Evolutionary Perspectives on Molecular Medicine: Cancer from an Evolutionary Perspective ANYA PLUTYNSKI

      part |2 pages

      Part III Representation and Modeling

      chapter 7|18 pages

      Toward a Notion of Intervention in Big-Data Biology and Molecular Medicine

      ByFEDERICO BOEM, EMANUELE RATTI

      chapter 8|27 pages

      Pathways to the Clinic: Cancer Stem Cells and Challenges for Translational Research

      ByMELINDA BONNIE FAGAN

      chapter 9|23 pages

      Counterfactual Reasoning in Molecular Medicine

      ByMARCO J. NATHAN

      part |2 pages

      Part IV Inference

      chapter 10|19 pages

      Forms of Extrapolation in Molecular Medicine

      ByPIERRE-LUC GERMAIN AND TUDOR BAETU

      chapter 11|16 pages

      Testing Oncological Treatments in the Era of Personalized Medicine

      ByDAVID TEIRA

      chapter 12|31 pages

      Opportunities and Challenges of Molecular Epidemiology

      ByFEDERICA RUSSO, PAOLO VINEIS
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