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Book

Inhalation Aerosols

Book

Inhalation Aerosols

DOI link for Inhalation Aerosols

Inhalation Aerosols book

Physical and Biological Basis for Therapy

Inhalation Aerosols

DOI link for Inhalation Aerosols

Inhalation Aerosols book

Physical and Biological Basis for Therapy
Edited ByAnthony J. Hickey, Heidi M. Mansour
Edition 3rd Edition
First Published 2019
eBook Published 25 March 2019
Pub. Location Boca Raton
Imprint CRC Press
DOI https://doi.org/10.1201/9781315159768
Pages 435
eBook ISBN 9781315159768
Subjects Medicine, Dentistry, Nursing & Allied Health
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Hickey, A.J., & Mansour, H.M. (Eds.). (2019). Inhalation Aerosols: Physical and Biological Basis for Therapy (3rd ed.). CRC Press. https://doi.org/10.1201/9781315159768

ABSTRACT

Inhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years.

In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section of the book uses the focus on disease and therapeutic agents to illustrate the application of specific technologies.

The final integrated strategies section draws the major points from the applications for disease targets and drug products.

TABLE OF CONTENTS

part Part I|1 pages

Fundamentals

chapter 1|28 pages

Physicochemical properties of respiratory particles and formulations

ByBoris Shekunov

chapter 2|10 pages

Particle deposition in the respiratory tract and the effect of respiratory disease

ByWilliam D. Bennett

chapter 3|15 pages

Mathematical modeling of inhaled therapeutic aerosol deposition in the respiratory tract

ByJeffry Schroeter, Bahman Asgharian, Julia Kimbell

chapter 4|13 pages

Lung transporters and absorption mechanisms in the lungs

ByMohammed Ali Selo, Hassan H.A. Al-Alak, Carsten Ehrhardt

chapter 5|35 pages

Bioavailability of inhaled compounds

ByLucila Garcia-Contreras

chapter 6|16 pages

3D models as tools for inhaled drug development

BySally-Ann Cryan, Jennifer Lorigan, Cian O’Leary

chapter 7|21 pages

Overview of the delivery technologies for inhalation aerosols

ByDaniel F. Moraga-Espinoza, Ashlee D. Brunaugh, Silvia Ferrati, Lara A. Heersema, Matthew J. Herpin, Patricia P. Martins, Hairui Zhang, Hugh D.C. Smyth

part Part II|2 pages

Applications, Influence of Lung Disease Pathophysiology on Aerosol Deposition, Inhaler Device Technique in Respiratory Disease, and Clinical Outcomes in Drug Performance Assessment

chapter 8|14 pages

Neonatal and pediatric inhalation drug delivery

ByAriel Berlinski

chapter 9|6 pages

Asthma

ByOmar S. Usmani

chapter 10|19 pages

Drug delivery in pulmonary aspergillosis

BySawittree Sahakijpijarn, Jay I. Peters, Robert O. Williams

chapter 11|28 pages

Lung cancer inhalation therapeutics

ByRajiv Dhand

chapter 12|8 pages

Inhaled therapeutics in chronic obstructive pulmonary disease

ByTejas Sinha, Paul Dejulio, Philip Diaz

chapter 13|15 pages

Cystic fibrosis infection and biofilm busters

ByJennifer Fiegel, Sachin Gharse

chapter 14|18 pages

Current and future CFTR therapeutics

ByMarne C. Hagemeijer, Gimano D. Amatngalim, Jeffrey M. Beekman

chapter 15|18 pages

Innate and adaptive barrier properties of airway mucus

ByAlison Schaefer, Samuel K. Lai

chapter 16|15 pages

Nontuberculous mycobacteria

ByM. Ghadiri, P.M. Young, D. Traini

chapter 17|11 pages

Inhalational therapies for non-cystic fibrosis bronchiectasis

ByAshvini Damodaran, Dustin R. Fraidenburg, Israel Rubinstein

chapter 18|10 pages

Pulmonary fibrosis

ByPriya Muralidharan, Don Hayes, Heidi M. Mansour

chapter 19|10 pages

Therapeutics in pulmonary hypertension

ByMaria F. Acosta, Don Hayes, Jeffrey R. Fineman, Jason X.-J. Yuan, Stephen M. Black, Heidi M. Mansour

chapter 20|4 pages

Overview of lung surfactant and respiratory distress syndrome

ByHeidi M. Mansour, Debra Droopad, Julie G. Ledford

chapter 21|16 pages

Surfactant aerosol therapy for nRDS and ARDS

ByDonovan B. Yeates

chapter 22|18 pages

Fundamentals in nasal drug delivery

ByZachary Warnken, Yu Jin Kim, Heidi M. Mansour, Robert O. Williams, Hugh D.C. Smyth

chapter 23|15 pages

Inhaled therapeutics against TB: The promise of pulmonary treatment and prevention strategies in the clinic

ByDominique N. Price, Nitesh K. Kunda, Elliott K. Miller, Pavan Muttil

part Part III|1 pages

Integrated Strategies (Reflecting Combined Elements from Chapters 8 through 23)

chapter 24|10 pages

Inhaled medication: Factors that affect lung deposition

ByJoy H. Conway

chapter 25|8 pages

A critical perspective on future developments based on the knowledge we have now

ByTania F. Bahamondez-Canas, Jasmim Leal, Hugh D.C. Smyth

chapter 26|8 pages

Ensuring effectiveness and reproducibility of inhaled drug treatment

ByAnthony J. Hickey

chapter 27|4 pages

Conclusion

ByAnthony J. Hickey, Heidi M. Mansour
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