Major presentation of pharmacokinetics by a leading international expert. Methods for: estimating drug disposition parameters from data obtained after intravascular or extravascular drug administration, estimating rate and extent of drug bioavailability, and comparing rate and extent of drug availability following administration of several different dosage forms of a drug.

chapter 1|14 pages

Simple Linear Models

chapter 2|30 pages

More Complicated Linear Models

chapter 3|18 pages

Complicated Linear Models

chapter 5|20 pages

Noncompartmental and System Analysis

chapter 6|8 pages

Linear Multiple Dose Equations

chapter 7|32 pages

Simple Nonlinear Models

chapter 8|8 pages

More Complicated Nonlinear Models

chapter 9|8 pages

Urinary Excretion

chapter 10|48 pages

Absorption Analysis and Bioavailability

chapter 11|18 pages

Physiological Pharmacokinetics

chapter 13|16 pages

Protein Binding

chapter 14|10 pages

Pharmacokinetic-Pharmacodynamic Modelling

chapter 15|12 pages

Metabolic Kinetics

chapter 17|6 pages

Measures of Fit