ABSTRACT
An estimated 30,000 children are born in the USA with congenital heart disease each year, two thirds of which will require corrective surgery. Medical advances have formed a trend of operating on newborns rather than waiting until the child is older. Ten years ago, the mortality for these operationswas 60% to 70%. That percentage has dropped to 2%. This specialized book explores the basic mechanisms of neurologic injury associated with congenital heart surgery while covering the emerging technologies for assessment of neurologic integrity and injury. The text also highlights the current and future techniques for reducing and preventing these injuries, and reviews the pertinent medicolegal issues.
TABLE OF CONTENTS
part I|73 pages
Development of the Central Nervous System
part II|113 pages
Assessment of CNS Function
part III|40 pages
Mechanisms of Neurological Injury
chapter Chapter 15|13 pages
Endothelial and White Cell Activation in Bypass and Reperfusion Injury: Brain Injury
part IV|48 pages
Clinical and Laboratory Studies of Cardiopulmonary Bypass, Hypothermia, and Circulatory Arrest
chapter Chapter 18|10 pages
Effects of CPB, Hypothermia, and Circulatory Arrest on Cerebral Blood Flow and Metabolism
chapter Chapter 20|135 pages
pH Management During Hypothermic Cardiopulmonary Bypass with Circulatory Arrest
part V|76 pages
A Prospective Clinical Study of Circulatory Arrest at Children’s Hospital, Boston
part VI|43 pages
New Strategies for Cerebral Protection