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      Book

      Molecular and Cellular Biology of Viruses
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      Book

      Molecular and Cellular Biology of Viruses

      DOI link for Molecular and Cellular Biology of Viruses

      Molecular and Cellular Biology of Viruses book

      Molecular and Cellular Biology of Viruses

      DOI link for Molecular and Cellular Biology of Viruses

      Molecular and Cellular Biology of Viruses book

      ByPhoebe Lostroh
      Edition 1st Edition
      First Published 2019
      eBook Published 12 July 2019
      Pub. Location New York
      Imprint Garland Science
      DOI https://doi.org/10.1201/9780429021725
      Pages 523
      eBook ISBN 9780429021725
      Subjects Bioscience
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      Lostroh, P. (2019). Molecular and Cellular Biology of Viruses (1st ed.). Garland Science. https://doi.org/10.1201/9780429021725

      ABSTRACT

      Viruses interact with host cells in ways that uniquely reveal a great deal about general aspects of molecular and cellular structure and function. Molecular and Cellular Biology of Viruses leads students on an exploration of viruses by supporting engaging and interactive learning. All the major classes of viruses are covered, with separate chapters for their replication and expression strategies, and chapters for mechanisms such as attachment that are independent of the virus genome type. Specific cases drawn from primary literature foster student engagement. End-of-chapter questions focus on analysis and interpretation with answers being given at the back of the book. Examples come from the most-studied and medically important viruses such as HIV, influenza, and poliovirus. Plant viruses and bacteriophages are also included. There are chapters on the overall effect of viral infection on the host cell. Coverage of the immune system is focused on the interplay between host defenses and viruses, with a separate chapter on medical applications such as anti-viral drugs and vaccine development. The final chapter is on virus diversity and evolution, incorporating contemporary insights from metagenomic research.

      Key selling feature:

      • Readable but rigorous coverage of the molecular and cellular biology of viruses
      • Molecular mechanisms of all major groups, including plant viruses and bacteriophages, illustrated by example
      • Host-pathogen interactions at the cellular and molecular level emphasized throughout
      • Medical implications and consequences included
      • Quality illustrations available to instructors
      • Extensive questions and answers for each chapter

      TABLE OF CONTENTS

      chapter 1|18 pages

      The Fundamentals of Molecular and Cellular Virology

      chapter 2|13 pages

      The Virus Replication Cycle

      chapter 3|43 pages

      Attachment, Penetration, and Uncoating

      chapter 4|47 pages

      Gene Expression and Genome Replication in Model Bacteriophages

      chapter 5|38 pages

      Gene Expression and Genome Replication in the Positive-Strand RNA Viruses

      chapter 6|22 pages

      Gene Expression and Genome Replication in the Negative-Strand RNA Viruses

      chapter 7|8 pages

      Gene Expression and Genome Replication in the Double-Stranded RNA Viruses

      chapter 8|48 pages

      Gene Expression and Genome Replication in the Double-Stranded DNA Viruses

      chapter 9|9 pages

      Gene Expression and Genome Replication in the Single-Stranded DNA Viruses

      chapter 10|25 pages

      Gene Expression and Genome Replication in the Retroviruses and Hepadnaviruses

      chapter 11|23 pages

      Assembly, Release, and Maturation

      chapter 12|16 pages

      Virus–Host Interactions during Lytic Growth

      chapter 13|27 pages

      Persistent Viral Infections

      chapter 14|20 pages

      Viral Evasion of Innate Host Defenses

      chapter 15|24 pages

      Viral Evasion of Adaptive Host Defenses

      chapter 16|30 pages

      Medical Applications of Molecular and Cellular Virology

      chapter 17|29 pages

      Viral Diversity, Origins, and Evolution

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