ABSTRACT
This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results.
TABLE OF CONTENTS
section Section I|1 pages
Broad Concepts and Analytic Techniques
section Section II|1 pages
Design
section Section III|1 pages
Analysis
section Section IV|1 pages
Communicating Results
chapter 16|19 pages
Guidelines for Statistical Reporting in Articles for Medical Journals*
Amplifications and Explanations
chapter 19|33 pages
The Importance of Beta, the Type II Error, and Sample Size in the Design and Interpretation of the Randomized Controlled Trial
Survey of Two Sets of “Negative” Trials
section Section V|1 pages
Reviews and Meta-Studies
chapter 22|14 pages
Combining Results from Independent Investigations
Meta-Analysis in Clinical Research
chapter 23|16 pages
Meta-Analyses of Randomized Control Trials
An Update of the Quality and Methodology
