ABSTRACT

The concept of epigenetics has been known about since the 1940s, but it is only in the last 10 years that research has shown just how wide ranging its effects are. It is now a very widely-used term, but there is still a lot of confusion surrounding what it actually is and does.Epigenetics is a new textbook that brings together the structure and mac

part Section 1

Basic Concepts

chapter Chapter One|6 pages

Introduction to the Study of Epigenetics

chapter Chapter Two|8 pages

The Basis of the Transcription Process

chapter Chapter Three|14 pages

DNA Packaging and Chromatin Architecture

chapter Chapter Four|10 pages

Modifying the Structure of Chromatin

chapter Chapter Five|20 pages

DNA Methylation

chapter Chapter Six|18 pages

Post-Translational Modification of Histones

chapter Chapter Seven|32 pages

Histone Modification Machinery

chapter Chapter Eight|19 pages

Locus-Specific Control of Histone-Modifying Enzyme Action

part Section 2|78 pages

Epigenetic Control of Cellular Function

chapter Chapter Nine|20 pages

Epigenetic Control of Cell-Specific Gene Expression

chapter Chapter Ten|8 pages

Epigenetic Control of the Mitotic Cell Cycle

chapter Chapter Eleven|14 pages

The Epigenetic Basis of Gene Imprinting

chapter Chapter Twelve|10 pages

Epigenetic Control of Cellular Differentiation

chapter Chapter Thirteen|25 pages

Reversibility of Epigenetic Modification Patterns

part Section 3|81 pages

The Epigenetic Basis of Disease

chapter Chapter Fifteen|18 pages

Epigenetics of Memory, Neurodegeneration, and Mental Health

chapter Chapter Sixteen|34 pages

Epigenetics of Cancer