ABSTRACT

First published in 1989, Immunology of Nude Mice presents a discussion of the nature of this viable laboratory mutant. This new volume updates all immunological information contained in the sparse literature concerning nude mice. It comprehensively explores some of the fre-quent questions associated with nude mice, such as if the mutant is really athymic or if the thymic defect causes all of the other deviations from brain to gonads. The practical consequences of hairlessness of the mutant are also consid-ered. Illustrated with original photographs and tables doc-umenting novel facts in immunology and physiology of nude mice, this publication is valuable for investigators and stu-dents entering the field.

chapter Chapter 1|3 pages

Introduction

The Contradictory Mouse

chapter Chapter 2|7 pages

The Nude Mutation

chapter Chapter 3|40 pages

The Thymic Defect

chapter Chapter 4|14 pages

T Cells

chapter Chapter 5|21 pages

B Cells and Immunoglobulins

chapter Chapter 6|8 pages

Stem Cells And Connective Tissues

chapter Chapter 7|14 pages

Phagocytic Systems And Native Resistance

chapter Chapter 8|19 pages

Lymphatic Tissues And Cellular Immune Reactions

chapter Chapter 9|9 pages

Hairlessness and Metabolic Compensations

chapter Chapter 10|18 pages

Neuroendocrine Regulations

chapter Chapter 11|2 pages

Nude Gene Transfer And Remutation

chapter Chapter 12|2 pages

Conclusions