ABSTRACT
Neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are a growing problem across the world’s aging population. Oxidative stress in the brain plays a central role in a common pathophysiology of these diseases. This book presents scientific research on the potential of antioxidant therapy in the prevention and treatment of neurodegenerative disorders.
This book outlines the roles of oxidative stress and diabetes mellitus in neurodegeneration, describes the molecular mechanisms of neurodegenerative disorders including the roles of environmental pollutants and inflammatory responses, and explores mitochondrial dysfunction. It then describes the protective abilities of antioxidants – including vitamin D, tocotrienol and coenzyme Q10 – against neurodegeneration. The book demonstrates the therapeutic potential of ketogenic diets, and highlights the roles of medicinal plants, phytopharmaceuticals, traditional medicines and food nutrients in neuroprotection.
Key Features:
- Explains damage caused by numerous neurodegenerative disorders and the possible protection offered by antioxidants and functional foods.
- Describes molecular mechanisms of neurodegeneration by oxidative stress, advancing age, diabetes and mitochondrial dysfunctions.
- Demonstrates protection offered by nutraceuticals, antioxidants, botanical extracts and functional foods.
The book contains twenty-three chapters divided into six sections written by leading researchers. This book is essential reading for health professionals, dietitians, food and nutrition scientists and anyone wanting to improve their knowledge of etiology of neurodegenerative diseases.
TABLE OF CONTENTS
part I|17 pages
Overview & Introduction
part II|108 pages
Molecular Mechanisms of Neurodegenerative Disorders, Inflammation, and Oxidative Stress
chapter 7|26 pages
Lipidomic Insight into Membrane Remodeling in Aging and Neurodegenerative Diseases
part III|48 pages
Mitochondrial Dysfunction and Neurodegeneration
part IV|82 pages
Redox Biology, Neurodegeneration, and Antioxidant Cytoprotection
part V|10 pages
Ketogenic Diets in Neuroprotection
part VI|169 pages
Medicinal Plants and Functional Foods in Neurodegenerative Disorders & Therapy
chapter 22|12 pages
Roles of Functional Foods and Nutraceuticals in Neuroprotection
part VII|5 pages
Commentary from the Editor’s Desk