ABSTRACT

Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology. In addition, the text also provides in-depth discussions of RNA structure for nanoparticle construction, RNA computation and modeling, single molecule imaging of RNA, RNA nanoparticle assembly, RNA nanoparticles in therapeutics, immunorecognition of RNA nanomaterials, RNA chemistry for nanoparticle synthesis, and conjugation and labeling.

  • Presents the latest research and discoveries in RNA nanotechnology
  • Features contributions from world-class experts in the field
  • Covers RNA nanoparticles in therapeutics
  • Describes self-assembled RNA nanoparticles

part I|70 pages

Concepts and Definitions in RNA Nanotechnology

chapter 1|2 pages

RNA Structure and Folding

chapter 9|1 pages

SELEX

part II|158 pages

Design, Synthesis, and Characterization Methods in RNA Nanotechnology

chapter 16|9 pages

HyperFold

A Web Server for Predicting Nucleic Acid Complexes

chapter 17|4 pages

RNA Switches

Towards Conditional Dynamic RNA-Based Constructs for Therapeutics and Bioassays

part III|61 pages

Immunorecognition of RNA Nanoparticles

part IV|154 pages

Delivery of Functional RNA Nanoparticles

chapter 39|6 pages

Extracellular Vesicles (EVs)

An Innovative Approach to Engineering Nucleic Acid Delivery

chapter 40|46 pages

Extracellular Vesicles (EVs)

Naturally Occurring Vehicles for RNA Nanotherapeutics

part V|164 pages

Application and Exploitation in RNA Nanotechnology

chapter 47|10 pages

MicroRNAs

Biology and Role in RNA Nanotechnology