ABSTRACT

This reference spotlights the immunologic aspects of applying interferon-gamma to the treatment of infectious diseases - revealing the current knowledge of the biology and potential utility of interferon-gamma.;Written by more than 30 leading investigators in the field, Anti-Infective Applications of Interferon-Gamma: presents information according to specific patient populations and pathogens; focuses on only the most promising of emerging therapeutic agents; furnishes a detailed update of the pleiotropic role of interferon-gamma in host defense; and studies clinical and preclinical experiences in a broad variety of disease indications.;Containing over 900 bibliographic citations for further research, this book should be useful for infectious disease specialists, pharmacologists, immunologists, surgeons, pediatricians, parasitologists, hematologists, virologists, microbiologists, pathologists, oncologists and tropical medicine specialists.

chapter 1|8 pages

The Interferons

A Clinical Overview

part II|208 pages

Target Infections

chapter 10|10 pages

Interferon-Gamma and Immunity to Malaria Sporozoites

Implications for the Development of Synthetic Vaccines

chapter 12|12 pages

Herpes Simplex as a Target for Anti-Infective Applications of Interferon-Gamma

Preclinical In Vitro and In Vivo Observations

chapter 17|14 pages

Influence of Interferon-Gamma on Legionella pneumophila

Mononuclear Phagocyte Interaction

part III|16 pages

Target Treatment Strategies