ABSTRACT
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects.
The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
TABLE OF CONTENTS
part I|153 pages
Biology of Skin and Hair of Laboratory Mice and Human Beings
part II|378 pages
Animal Models of Genetic Based Skin Diseases
section Section A|325 pages
Mouse Single Gene Mutations
section Section B|25 pages
Purported Polygenic Mouse Skin Diseases
section Section C|26 pages
Nonmurine Animal Models of Genetic Based Skin Diseases