ABSTRACT

Sequencing genetic material is now common practice. The general population have become consumers of this information but without an understanding of the biological processes that render sequencing data useful. The interpretation of genetic sequence depends on an appreciation of the basics of genetics and the limits of such data. This book provides the background necessary to understand, interpret, and apply sequencing information to real- world problems. Replication of genetic material, the structure of DNA, typing methods, and forensic applications are all discussed in this useful primer.

Key Features

• Provides self-learning about DNA fingerprinting.

• Includes sections on how to analyze and interpret DNA fingerprinting.

• Covers legal and medicolegal issues and case analyses.

• Teaches novice legal community about DNA fingerprints.

• Summarizes for a general audience the role of ancestry, DNA, and what that means.

chapter |2 pages

Introduction

chapter Chapter 1|7 pages

The Cell

chapter Chapter 3|27 pages

Structure of DNA and Why We Use DNA in Forensic Science

What Are Small Tandem Repeats (STRs), and Why Do We Use Them?

chapter Chapter 5|8 pages

Sex Determination by STR

chapter Chapter 6|6 pages

The Combined DNA Index System (CODIS)

chapter Chapter 7|12 pages

How STRs Are Analyzed in a Forensic Laboratory

chapter Chapter 8|8 pages

Complexities of Sex Determination

chapter Chapter 9|8 pages

Y-STR and Paternal Ancestry

chapter Chapter 10|14 pages

Mitochondrial STRs

chapter Chapter 11|16 pages

Forensic Serology

Whose Blood Is This? Is It Human?

chapter Chapter 13|18 pages

A Simple Guide for Understanding the Value of DNA Results

A Short Discussion on Probability and Statistical Calculations