ABSTRACT

The use of different foods, herbs, and spices to treat or prevent disease has been recorded for thousands of years. Egyptian papyrus, hieroglyphics and ancient texts from the Middle East have described the cultivation and preparations of herbs and botanicals to “cure the sick.” There are even older records from China and India. Some ancient scripts describe the use of medicinal plants which have never been seen within European cultures. Indeed, all ancient civilizations have pictorial records of different foods, herbs, and spices being used for medical purposes. However, there are fundamental questions pertaining to the scientific evidence for the use of these agents or their extracts in modern medicine.

There have been considerable advances in scientific techniques over the last few decades. These have been used to examine the composition and applications of traditional cures. Modern science has also seen the investigation of herbs, spices and botanicals beyond their traditional usage. For example, plants which have been used for “digestion” or “medical ills” since time immemorial are now being investigated for anti-cancer properties or their toxicity, using high throughput screening. Techniques also include molecular biology, cellular biochemistry, physiology, endocrinology and even medical imaging. However, much of the material relating to the scientific basis or applications of traditional foods, herbs, spices and botanicals is scattered among various sources. The widespread applicability of foods or botanicals is rarely described and cautionary notes on toxicity are often ignored. These questions are explored in Ancient and Traditional Foods, Plants, Herbs and Spices used in Cancer.

Features

  • Provides an evidenced-based approach in describing usage and applications of traditional foods and botanicals in prevention and treatment of cancer
  • Contains chapters on biomedical research related to cancer studies
  • Discusses extraction and analysis of active agents, in vitro studies, pre-clinical investigations in animals, and clinical studies
  • Bridges modern day sciences with historical backgrounds related to foods and plants

With contributions from leading international experts including those from world renowned institutions, this book is a reference for oncologists, physicians, health scientists, healthcare workers, pharmacologists, and research scientists.

section Section I|86 pages

Overviews and Dietary Components

chapter 1|16 pages

Ginsenosides and Hepatic Cancer

A Review of Preclinical and Clinical Studies

section Section II|225 pages

Specific Agents, Items and Extracts

chapter 9|16 pages

Barberry (Berberis vulgaris)

Composition and Use of Extracts in Cancer Studies

chapter 10|14 pages

Chuanxinlian/Kalmegh (Andrographis paniculata (Burm.f.) Nees)

Discoveries in Esophageal, Gastric and Colorectal Cancer Studies

chapter 11|8 pages

Crisp-Leaved Fleabane (Pulicaria undulata)

Molecular Actions and Pathways in Tumor Cells

chapter 13|16 pages

Giant Angelica

Angelica gigas Nakai – Herbal Giant's Anticancer Potential

chapter 15|10 pages

Love Apple (Paris polyphylla Smith) and Oral Cancer Investigations

Antiproliferative and Apoptosis-Inducing Effects of Phytochemical Agents on Oral Cancer Cells

chapter 16|12 pages

Papaya (Carica papaya L.) as an Effective Adjuvant to Cancer Therapy

Phytochemical Profile, Cellular and Molecular Targets

chapter 17|16 pages

Plum Mango (Bouea macrophylla)

Compositional Profile and Usage in Cancer

chapter 18|18 pages

Sabah Snake Grass (Clinacanthus nutans) and Its Anticancer Activity

Phytochemical Composition and Signaling Pathways

chapter 20|14 pages

Self-Heal (Prunella vulgaris L.)

In Vitro and In Vivo Aspects of Anticancer Activity in Different Cancers

chapter 21|16 pages

Lichen, Pseudevernia furfuracea (L.) Zopf

Analytical Compositional Features, Biological Activity and Use in Cancer Studies

chapter 22|15 pages

Turmeric (Curcuma longa) and Applications to Cancer Studies

A Focus on the Molecular Effects of Curcumin in Colorectal Cancer