ABSTRACT
Much of the biology of oxidative stress and oxidative signalling centres on the generation and handling of hydrogen peroxide. The overall aim for this book would be to provide an insightful and useful forum to assist with the understanding of the relevance of hydrogen peroxide generation and how this is managed in human biology. The target audience would be those who currently have an interest in the generation of ROS, but who do not have expertise in chemistry, as well as those experts in the chemistry of oxidative stress, but without detailed understanding of the biologically relevant setting. We would aim to bridge the gap in understanding between chemistry and biology.
TABLE OF CONTENTS
section I|145 pages
Chemistry and Biochemistry of H2O2
chapter 1|14 pages
Hydrogen Peroxide, a Molecule with a Janus Face
section II|131 pages
Biological Sources of H2O2
section III|72 pages
Myeloperoxidase and Derived Oxidants
chapter 12|22 pages
Myeloperoxidase-Derived Oxidants Hypochlorous Acid and Chloramines
section IV|98 pages
H2O2 in Cellular Metabolism and Signaling