ABSTRACT
This volume presents a snapshot of some of the most important ongoing research in cancer. With cancer as the second leading cause of death worldwide, extensive research is going on globally to decipher the molecular mechanism underlying cancer that will help in finding better targets for drug therapy. The book brings together new research on molecular mechanism and cancer therapeutics in one place. With chapters from experts in their respective fields, chapters cover molecular mechanisms, etiology, prognosis, detection, and treatment of cancer. Emphasis has been given to the intricate mechanism behind the deregulation of cell division, disruption of cell cycle check points, mutation in oncogenes and tumor suppressor genes, apoptosis, and erratic cell signaling. The book discusses in detail topics such as angiogenesis and tumor microenvironment, which are increasingly receiving attention, especially in the field of neoplastic vascularization and metastasis. The book also includes chapters detailing the current understanding and the future perspective of cancer stem cells.
TABLE OF CONTENTS
part |2 pages
PART I MOLECULAR MECHANISMSUNDERLYING INITIATION,PROMOTION, AND PROGRESSIONOF CANCER
part |2 pages
PART II CANCER ETIOLOGY: PHYSICAL,CHEMICAL, ENVIRONMENTALFACTORS AND GENETICSUSCEPTIBILITY
part |2 pages
PART III CANCER PREVENTION ANDCONVENTIONAL THERAPIES
part |2 pages
PART IV NOVEL THERAPEUTIC APPROACHESFOR CANCER