ABSTRACT
This landmark volume discusses the characteristics and impact of the remodeling process on airway function and clinical disease expression within the airway in asthma, covering pharmacological therapies and possible future targets relevant to regulating the remodeling process.
Emphasizes the importance of treating underlying airway inflammat
TABLE OF CONTENTS
chapter 1|4 pages
What Does Airway Remodeling Mean? Its Relevance to Asthma
JEAN BOUSQUET ANTONIO MAURIZIO VIGNOLA INSERM U454 Palermo, Italy Villeneuve
chapter 2|22 pages
How Can We Assess Airway Remodeling Using Imaging?
DANY JAFFUEL JEAN BOUSQUET Montpellier University and Service des Mala dies Respiratoires- Villeneuve INSERM U454 Villeneuve FABRICE JEAN PAGANIN n, France
chapter 4|12 pages
Physiological Consequences of Lung Remodeling in Asthma
BJORN JONSON Lund I. Introduction
chapter 5|22 pages
Consequences of Airway Remodeling to the Patient
Helsinki University and ity Central Hospital I. Introduction
chapter 6|34 pages
Signaling Mechanisms That Regulate Airway Smooth Muscle Cell Function and Growth Aili L. Lazaar and Reynold A . Panettieri, Jr
Medical Center
chapter 7|24 pages
The Bronchial Vessels in Airway Remodeling
JOHN W. WILSON and XUN LI The Alfred Campus I. Introduction
chapter 8|10 pages
The Extracellular Matrix of the Airways and Bronchial Asthma
WILLIAM R. ROCHE l Hospital Southampton, England
chapter 9|20 pages
Role of the Airway Nervous System in Airway Remodeling
TONY R. BAI DARRYL A. KNIGHT lumbia U tralia Vancouver, British Columbia, Canada I. Introduction
chapter 10|22 pages
The Influence of Pharmacological Therapy on Airway Remodeling in Asthma
PETER H. HOWARTH Hospital I. Introduction
chapter 11|12 pages
The Human Eosinophil and Its Role in Airway Remodeling
PER VENGE sala I. Introduction
chapter 12|16 pages
Role of Macrophages in Airway Remodeling in Asthma
Service des Maladies Respiratoires- INSERM U454 Institute of Lung Pathophysiology Hopital Arnaud de Villeneuve
chapter 13|28 pages
Airway Smooth Muscle as a Target for Novel Antiasthma Drugs Acting on Airway Wall Remodeling
ALASTAIR G. STEWART University of Melbourne Parkville, Victoria, Australia
chapter 14|16 pages
Growth Factor-Extracellular Matrix Interactions in Bronchial Tissue in Asthma
JANIS K. SHUTE Hospital I. Introduction
chapter 15|10 pages
Is There an Animal Model of Airway Remodeling? A . Pauwels
JOHAN C. KIPS and ELS PALMANS and ROMAIN A. PAUWELS NELE VANACKER ity Hospital Ghent, Belgium I. Introduction